Port site metastases after minimally invasive resection for colorectal cancer: A retrospective study of 13 patients.
Port site metastases after minimally invasive resection for colorectal cancer: A retrospective study of 13 patients.
- 2019
BACKGROUND: Minimally invasive surgeries are increasingly being performed for primary colon cancer resections since laparoscopic and robotic surgeries have less post-operative pain, shorter length of hospitalization, less morbidity, improved patient satisfaction and equivalent R0 resection rates compared to laparotomy. CONCLUSIONS: Port site metastases were present concomitantly with peritoneal metastases in 13 patients. An advanced T-stage of disease occurred in 85% of patients. Port site metastases do occur after minimally invasive colon resection. Copyright © 2019 Elsevier Ltd. All rights reserved. METHODS: To analyze characteristics of patients who developed port site metastases after minimally invasive colectomy, a retrospective case series of a single institution from 2004 to 2017 was performed. The study included patients who had a minimally invasive resection of the primary colon cancer and subsequent cytoreduction and heated intraperitoneal chemotherapy (CRS/HIPEC) for peritoneal metastases. Patient characteristics, histology, pathology, prior treatments, time between surgeries, carcinoembryonic antigen (CEA) levels and survival were reviewed. RESULTS: There were 123 patients who had CRS/HIPEC and 13 of them had a history of laparoscopic or robotic colectomy followed by the development of port site disease. Four were females, nine were males. Median age was 48 years (range, 19-64). Eleven of 13 primary colon cancers were T3 or T4. Ten of 13 patients had no clinical evidence of peritoneal metastases at the time of initial resection. All 13 patients had metastatic deposits at port sites that were confirmed histopathologically at the time of CRS/HIPEC.
English
0960-7404
10.1016/j.suronc.2019.02.008 [doi] S0960-7404(18)30445-6 [pii]
*Colorectal Neoplasms/su [Surgery]
*Laparoscopy/ae [Adverse Effects]
*Minimally Invasive Surgical Procedures/ae [Adverse Effects]
*Peritoneal Neoplasms/ep [Epidemiology]
*Peritoneal Neoplasms/sc [Secondary]
*Postoperative Complications
Adult
Colorectal Neoplasms/pa [Pathology]
Female
Follow-Up Studies
Humans
Incidence
Male
Middle Aged
Prognosis
Retrospective Studies
Survival Rate
Young Adult
Washington Cancer Institute
Journal Article
BACKGROUND: Minimally invasive surgeries are increasingly being performed for primary colon cancer resections since laparoscopic and robotic surgeries have less post-operative pain, shorter length of hospitalization, less morbidity, improved patient satisfaction and equivalent R0 resection rates compared to laparotomy. CONCLUSIONS: Port site metastases were present concomitantly with peritoneal metastases in 13 patients. An advanced T-stage of disease occurred in 85% of patients. Port site metastases do occur after minimally invasive colon resection. Copyright © 2019 Elsevier Ltd. All rights reserved. METHODS: To analyze characteristics of patients who developed port site metastases after minimally invasive colectomy, a retrospective case series of a single institution from 2004 to 2017 was performed. The study included patients who had a minimally invasive resection of the primary colon cancer and subsequent cytoreduction and heated intraperitoneal chemotherapy (CRS/HIPEC) for peritoneal metastases. Patient characteristics, histology, pathology, prior treatments, time between surgeries, carcinoembryonic antigen (CEA) levels and survival were reviewed. RESULTS: There were 123 patients who had CRS/HIPEC and 13 of them had a history of laparoscopic or robotic colectomy followed by the development of port site disease. Four were females, nine were males. Median age was 48 years (range, 19-64). Eleven of 13 primary colon cancers were T3 or T4. Ten of 13 patients had no clinical evidence of peritoneal metastases at the time of initial resection. All 13 patients had metastatic deposits at port sites that were confirmed histopathologically at the time of CRS/HIPEC.
English
0960-7404
10.1016/j.suronc.2019.02.008 [doi] S0960-7404(18)30445-6 [pii]
*Colorectal Neoplasms/su [Surgery]
*Laparoscopy/ae [Adverse Effects]
*Minimally Invasive Surgical Procedures/ae [Adverse Effects]
*Peritoneal Neoplasms/ep [Epidemiology]
*Peritoneal Neoplasms/sc [Secondary]
*Postoperative Complications
Adult
Colorectal Neoplasms/pa [Pathology]
Female
Follow-Up Studies
Humans
Incidence
Male
Middle Aged
Prognosis
Retrospective Studies
Survival Rate
Young Adult
Washington Cancer Institute
Journal Article