Timing of radiation therapy in nipple-sparing mastectomy influences outcomes and patient-reported quality of life. (Record no. 10771)
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000 -LEADER | |
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fixed length control field | 02540nam a22003257a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 180619s20182018 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
International Standard Serial Number | 1075-122X |
024 ## - OTHER STANDARD IDENTIFIER | |
Standard number or code | 10.1111/tbj.13066 [doi] |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
PMID | 29781241 |
245 ## - TITLE STATEMENT | |
Title | Timing of radiation therapy in nipple-sparing mastectomy influences outcomes and patient-reported quality of life. |
251 ## - Source | |
Source | Breast Journal. 2018 May 20 |
252 ## - Abbreviated Source | |
Abbreviated source | Breast J. 2018 May 20 |
253 ## - Journal Name | |
Journal name | The breast journal |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Year | 2018 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Manufacturer | FY2018 |
266 ## - Date added to catalog | |
Date added to catalog | 2018-06-19 |
520 ## - SUMMARY, ETC. | |
Abstract | Copyright (c) 2018 Wiley Periodicals, Inc. |
520 ## - SUMMARY, ETC. | |
Abstract | The aim of this study is to assess the complication profile and impact on patient-reported quality of life in those undergoing nipple-sparing mastectomy (NSM) with immediate breast reconstruction and subsequent prosthetic reconstruction in patients with prior breast radiation therapy (pRT) vs those receiving adjuvant post-mastectomy radiation therapy (PMRT). An IRB-approved, retrospective analysis was performed from 2002 to 2014 to identify NSM patients that underwent pRT or PMRT. A 22-item Likert scale questionnaire was administered by a third party to register patient-reported quality of life. Forty patients met criteria for outcomes analysis, and 30 patients answered the questionnaire. Mean age was 45.6 years old and mean follow-up was 3.8 years. Complication rates for the PMRT cohort were 61.9% vs 31.6% in the pRT cohort, P = .067, and those requiring operative intervention were PMRT 38.1% vs pRT 5.3%, P = .021. Nipple-areolar complex survival was 100% in the pRT vs 85.7% in the PMRT, P = .233. Breast-related quality of life scores were superior in the pRT group within multiple domains. Patients are more likely to develop complications requiring an operative intervention and have decreased breast-related quality of life when undergoing NSM with PMRT compared to patients undergoing NSM having received pRT. |
546 ## - LANGUAGE NOTE | |
Language note | English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
Institution | MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION | |
Department | Surgery/General Surgery |
657 ## - INDEX TERM--FUNCTION | |
Medline publication type | Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Local Authors | Sosin, Michael |
790 ## - Authors | |
All authors | Bartholomew AJ, Cox SE, Gulla A, Pittman TA, Potdevin L, Seevaratnam S, Sigdel M, Sosin M, Tousimis EA, Willey SC |
856 ## - ELECTRONIC LOCATION AND ACCESS | |
DOI | <a href="https://dx.doi.org/10.1111/tbj.13066">https://dx.doi.org/10.1111/tbj.13066</a> |
Public note | https://dx.doi.org/10.1111/tbj.13066 |
858 ## - ORCID | |
ORCID text | Sosin, Michael |
Orcid | <a href="http://orcid.org/0000-0001-5831-8503">http://orcid.org/0000-0001-5831-8503</a> |
Name | http://orcid.org/0000-0001-5831-8503 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Koha item type | Journal Article |
Item type description | Article |
Withdrawn status | Lost status | Damaged status | Not for loan | Collection | Home library | Current library | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
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MedStar Authors Catalog | MedStar Authors Catalog | 06/19/2018 | 29781241 | 29781241 | 06/19/2018 | 06/19/2018 | Journal Article |