Timing of radiation therapy in nipple-sparing mastectomy influences outcomes and patient-reported quality of life. (Record no. 10771)

MARC details
000 -LEADER
fixed length control field 02540nam a22003257a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 180619s20182018 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1075-122X
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1111/tbj.13066 [doi]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 29781241
245 ## - TITLE STATEMENT
Title Timing of radiation therapy in nipple-sparing mastectomy influences outcomes and patient-reported quality of life.
251 ## - Source
Source Breast Journal. 2018 May 20
252 ## - Abbreviated Source
Abbreviated source Breast J. 2018 May 20
253 ## - Journal Name
Journal name The breast journal
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2018
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2018
266 ## - Date added to catalog
Date added to catalog 2018-06-19
520 ## - SUMMARY, ETC.
Abstract Copyright (c) 2018 Wiley Periodicals, Inc.
520 ## - SUMMARY, ETC.
Abstract The aim of this study is to assess the complication profile and impact on patient-reported quality of life in those undergoing nipple-sparing mastectomy (NSM) with immediate breast reconstruction and subsequent prosthetic reconstruction in patients with prior breast radiation therapy (pRT) vs those receiving adjuvant post-mastectomy radiation therapy (PMRT). An IRB-approved, retrospective analysis was performed from 2002 to 2014 to identify NSM patients that underwent pRT or PMRT. A 22-item Likert scale questionnaire was administered by a third party to register patient-reported quality of life. Forty patients met criteria for outcomes analysis, and 30 patients answered the questionnaire. Mean age was 45.6 years old and mean follow-up was 3.8 years. Complication rates for the PMRT cohort were 61.9% vs 31.6% in the pRT cohort, P = .067, and those requiring operative intervention were PMRT 38.1% vs pRT 5.3%, P = .021. Nipple-areolar complex survival was 100% in the pRT vs 85.7% in the PMRT, P = .233. Breast-related quality of life scores were superior in the pRT group within multiple domains. Patients are more likely to develop complications requiring an operative intervention and have decreased breast-related quality of life when undergoing NSM with PMRT compared to patients undergoing NSM having received pRT.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Surgery/General Surgery
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Sosin, Michael
790 ## - Authors
All authors Bartholomew AJ, Cox SE, Gulla A, Pittman TA, Potdevin L, Seevaratnam S, Sigdel M, Sosin M, Tousimis EA, Willey SC
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1111/tbj.13066">https://dx.doi.org/10.1111/tbj.13066</a>
Public note https://dx.doi.org/10.1111/tbj.13066
858 ## - ORCID
ORCID text Sosin, Michael
Orcid <a href="http://orcid.org/0000-0001-5831-8503">http://orcid.org/0000-0001-5831-8503</a>
Name http://orcid.org/0000-0001-5831-8503
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 06/19/2018   29781241 29781241 06/19/2018 06/19/2018 Journal Article

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