Epidemiological Characterization of a Directed and Weighted Disease Network Using Data From a Cohort of One Million Patients: Network Analysis. (Record no. 11198)

MARC details
000 -LEADER
fixed length control field 04238nam a22005297a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200709s20202020 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1438-8871
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.2196/15196 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC7180516 [pmc]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code v22i4e15196 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 32271154
245 ## - TITLE STATEMENT
Title Epidemiological Characterization of a Directed and Weighted Disease Network Using Data From a Cohort of One Million Patients: Network Analysis.
251 ## - Source
Source Journal of Medical Internet Research. 22(4):e15196, 2020 04 09.
252 ## - Abbreviated Source
Abbreviated source J Med Internet Res. 22(4):e15196, 2020 04 09.
252 ## - Abbreviated Source
Former abbreviated source J Med Internet Res. 22(4):e15196, 2020 Apr 09.
253 ## - Journal Name
Journal name Journal of medical Internet research
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2020
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2020
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status epublish
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status epublish
266 ## - Date added to catalog
Date added to catalog 2020-07-09
268 ## - Previous citation
-- Journal of Medical Internet Research. 22(4):e15196, 2020 Apr 09.
501 ## - WITH NOTE
Local holdings Available online from MWHC library: 1999 - present
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: In the past 20 years, various methods have been introduced to construct disease networks. However, established disease networks have not been clinically useful to date because of differences among demographic factors, as well as the temporal order and intensity among disease-disease associations.
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: We constructed a directional and weighted disease network visualizing demographic factors. Our proposed disease network model is expected to be a valuable tool for use by early clinical researchers seeking to explore the relationships among diseases in the future. Copyright (c)Kyungmin Ko, Chae Won Lee, Sangmin Nam, Song Vogue Ahn, Jung Ho Bae, Chi Yong Ban, Jongman Yoo, Jungmin Park, Hyun Wook Han. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 09.04.2020.
520 ## - SUMMARY, ETC.
Abstract METHODS: We used National Health Insurance Service-National Sample Cohort (NHIS-NSC) data from the Republic of Korea, which included the time series insurance information of 1 million out of 50 million Korean (approximately 2%) patients obtained between 2002 and 2013. After setting the observation and outcome periods, we selected only 520 common Korean Classification of Disease, sixth revision codes that were the most prevalent diagnoses, making up approximately 80% of the cases, for statistical validity. Using these data, we constructed a directional and weighted temporal network that considered both demographic factors and network properties.
520 ## - SUMMARY, ETC.
Abstract OBJECTIVE: This study sought to investigate the overall patterns of the associations among diseases; network properties, such as clustering, degree, and strength; and the relationship between the structure of disease networks and demographic factors.
520 ## - SUMMARY, ETC.
Abstract RESULTS: Our disease network contained 294 nodes and 3085 edges, a relative risk value of more than 4, and a false discovery rate-adjusted P value of <.001. Interestingly, our network presented four large clusters. Analysis of the network topology revealed a stronger correlation between in-strength and out-strength than between in-degree and out-degree. Further, the mean age of each disease population was related to the position along the regression line of the out/in-strength plot. Conversely, clustering analysis suggested that our network boasted four large clusters with different sex, age, and disease categories.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Community Networks/st [Standards]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cohort Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Data Analysis
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Middle Aged
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Pathology
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Ko, Kyungmin
790 ## - Authors
All authors Ahn SV, Bae JH, Ban CY, Han HW, Ko K, Lee CW, Nam S, Park J, Yoo J
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.2196/15196">https://dx.doi.org/10.2196/15196</a>
Public note https://dx.doi.org/10.2196/15196
-- https://dx.doi.org/10.2196/15196
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.2196/15196">https://dx.doi.org/10.2196/15196</a>
Public note https://dx.doi.org/10.2196/15196
-- https://dx.doi.org/10.2196/15196
858 ## - ORCID
ORCID text Ko, Kyungmin
Orcid <a href="https://orcid.org/0000-0001-5736-409X">https://orcid.org/0000-0001-5736-409X</a>
Name https://orcid.org/0000-0001-5736-409X
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 07/09/2020   32271154 32271154 07/09/2020 07/09/2020 Journal Article

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