MARC details
000 -LEADER |
fixed length control field |
03033nam a22004217a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
210217s20212021 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
2038-0305 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1186/s13317-020-00143-z [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1186/s13317-020-00143-z [pii] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
PMC7788985 [pmc] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
33407881 |
245 ## - TITLE STATEMENT |
Title |
ANCA-negative microscopic polyangiitis with diffuse alveolar hemorrhage masquerading as congestive heart failure. |
251 ## - Source |
Source |
Autoimmunity Highlights. 12(1):1, 2021 Jan 06. |
252 ## - Abbreviated Source |
Abbreviated source |
Autoimmunity Highlights. 12(1):1, 2021 Jan 06. |
253 ## - Journal Name |
Journal name |
Auto- immunity highlights |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2021 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2021 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
epublish |
266 ## - Date added to catalog |
Date added to catalog |
2021-02-17 |
520 ## - SUMMARY, ETC. |
Abstract |
BACKGROUND: Microscopic polyangiitis (MPA) is a subtype of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV), involving small and medium sized vessels, often affecting the kidneys and lungs. Anti-neutrophil cytoplasmic antibody (ANCA) is detected in up to 90% of cases of MPA and its detection helps guide diagnosis, however cases of ANCA-negative MPA have been reported, hence definitive diagnosis relies on tissue biopsy. |
520 ## - SUMMARY, ETC. |
Abstract |
CASE REPORT: A 23-year-old man was evaluated for dyspnea and pleuritic chest pain, and found to have bilateral intra-alveolar opacities and hilar adenopathy. Diagnostic work up revealed positive anti-nuclear antibodies (ANA) and negative ANCA, which in the setting of a non-classical presentation, delayed diagnosis and appropriate treatment. Due to persistent symptoms and a high suspicion for autoimmune disease with pulmonary-renal syndrome, he underwent lung biopsy which revealed intra-alveolar hemorrhage and capillaritis indicative of microscopic polyangiitis (MPA). Surprisingly, kidney biopsy was not typical of classic MPA, but revealed less common features. Due to therapeutic noncompliance he was readmitted multiple times thereafter with rare complications of MPA such as acute pancreatitis and hemorrhagic pericardial effusion with tamponade. |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSION: This case serves as an important clinical reminder to consider AAV even in those with negative ANCA serologies and a high suspicion for pulmonary-renal syndrome. It also demonstrates the high morbidity in cases of diagnostic delay and inadequate treatment. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Franklin Square Medical Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
MedStar Health Baltimore Residents |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Aloor, Rohit |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Chan, Nina |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Haas, Christopher J |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Iding, Jeffery S |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Mollaeian, Arash |
790 ## - Authors |
All authors |
Aloor R, Arend LJ, Chan N, Haas CJ, Iding JS, Mollaeian A, Saeidabadi SHF |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1186/s13317-020-00143-z">https://dx.doi.org/10.1186/s13317-020-00143-z</a> |
Public note |
https://dx.doi.org/10.1186/s13317-020-00143-z |
858 ## - ORCID |
ORCID text |
Mollaeian, Arash |
Orcid |
<a href="http://orcid.org/0000-0002-1483-2241">http://orcid.org/0000-0002-1483-2241</a> |
Name |
http://orcid.org/0000-0002-1483-2241 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |