ANCA-negative microscopic polyangiitis with diffuse alveolar hemorrhage masquerading as congestive heart failure. (Record no. 11216)

MARC details
000 -LEADER
fixed length control field 03033nam a22004217a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 210217s20212021 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2038-0305
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1186/s13317-020-00143-z [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1186/s13317-020-00143-z [pii]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC7788985 [pmc]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 33407881
245 ## - TITLE STATEMENT
Title ANCA-negative microscopic polyangiitis with diffuse alveolar hemorrhage masquerading as congestive heart failure.
251 ## - Source
Source Autoimmunity Highlights. 12(1):1, 2021 Jan 06.
252 ## - Abbreviated Source
Abbreviated source Autoimmunity Highlights. 12(1):1, 2021 Jan 06.
253 ## - Journal Name
Journal name Auto- immunity highlights
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2021
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2021
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status epublish
266 ## - Date added to catalog
Date added to catalog 2021-02-17
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Microscopic polyangiitis (MPA) is a subtype of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV), involving small and medium sized vessels, often affecting the kidneys and lungs. Anti-neutrophil cytoplasmic antibody (ANCA) is detected in up to 90% of cases of MPA and its detection helps guide diagnosis, however cases of ANCA-negative MPA have been reported, hence definitive diagnosis relies on tissue biopsy.
520 ## - SUMMARY, ETC.
Abstract CASE REPORT: A 23-year-old man was evaluated for dyspnea and pleuritic chest pain, and found to have bilateral intra-alveolar opacities and hilar adenopathy. Diagnostic work up revealed positive anti-nuclear antibodies (ANA) and negative ANCA, which in the setting of a non-classical presentation, delayed diagnosis and appropriate treatment. Due to persistent symptoms and a high suspicion for autoimmune disease with pulmonary-renal syndrome, he underwent lung biopsy which revealed intra-alveolar hemorrhage and capillaritis indicative of microscopic polyangiitis (MPA). Surprisingly, kidney biopsy was not typical of classic MPA, but revealed less common features. Due to therapeutic noncompliance he was readmitted multiple times thereafter with rare complications of MPA such as acute pancreatitis and hemorrhagic pericardial effusion with tamponade.
520 ## - SUMMARY, ETC.
Abstract CONCLUSION: This case serves as an important clinical reminder to consider AAV even in those with negative ANCA serologies and a high suspicion for pulmonary-renal syndrome. It also demonstrates the high morbidity in cases of diagnostic delay and inadequate treatment.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Franklin Square Medical Center
656 ## - INDEX TERM--OCCUPATION
Department MedStar Health Baltimore Residents
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Aloor, Rohit
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Chan, Nina
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Haas, Christopher J
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Iding, Jeffery S
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Mollaeian, Arash
790 ## - Authors
All authors Aloor R, Arend LJ, Chan N, Haas CJ, Iding JS, Mollaeian A, Saeidabadi SHF
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1186/s13317-020-00143-z">https://dx.doi.org/10.1186/s13317-020-00143-z</a>
Public note https://dx.doi.org/10.1186/s13317-020-00143-z
858 ## - ORCID
ORCID text Mollaeian, Arash
Orcid <a href="http://orcid.org/0000-0002-1483-2241">http://orcid.org/0000-0002-1483-2241</a>
Name http://orcid.org/0000-0002-1483-2241
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 02/17/2021   33407881 33407881 02/17/2021 02/17/2021 Journal Article

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