MARC details
| 000 -LEADER |
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| fixed length control field |
03172nam a22003737a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
191204s20192019 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
2515-5091 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1093/jncics/pkz054 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
pkz054 [pii] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
PMC6795232 [pmc] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
31737862 |
| 245 ## - TITLE STATEMENT |
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| Title |
Intentional Weight Loss and Obesity-Related Cancer Risk. |
| 251 ## - Source |
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| Source |
JNCI Cancer Spectrum. 3(4):pkz054, 2019 Dec. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
JNCI cancer spectr.. 3(4):pkz054, 2019 Dec. |
| 253 ## - Journal Name |
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| Journal name |
JNCI cancer spectrum |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2019 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2020 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
epublish |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2019-12-04 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Background: Epidemiologic studies regarding weight loss and subsequent cancer risk are sparse. The study aim was to evaluate the association between weight change by intentionality and obesity-related cancer incidence in the Women's Health Initiative Observational Study. Eleven cancers were considered obesity related: breast, ovary, endometrium, colon and rectum, esophagus, kidney, liver, multiple myeloma, pancreas, stomach, and thyroid. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Conclusion: Intentional weight or WC loss in postmenopausal women was associated with lower risk of obesity-related cancer. These findings suggest that postmenopausal women who intentionally lose weight can reduce their obesity-related cancer risk. Copyright (c) The Author(s) 2019. Published by Oxford University Press. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Methods: Postmenopausal women (n = 58 667) aged 50-79 years had body weight and waist circumference (WC) measured at baseline and year 3. Weight or WC change was categorized as stable (change < +/-5%), loss (>=5%), and gain (>=5%). Self-report at year 3 characterized weight loss as intentional or unintentional. During the subsequent 12 years (mean) of follow-up, 6033 incident obesity-related cancers were identified. Relationships were evaluated using multivariable Cox proportional hazards regression models. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Results: Compared to women with stable weight, women with intentional weight loss had lower obesity-related cancer risk (hazard ratio [HR] = 0.88, 95% confidence interval [CI] = 0.80 to 0.98). A similar result was observed for intentional WC reduction (HR = 0.88, 95% CI = 0.80 to 0.96). Among all cancers, intentional weight loss was most strongly associated with endometrial cancer (HR = 0.61, 95% CI = 0.42 to 0.88). Intentional WC loss was also associated with lower colorectal cancer risk (HR = 0.79, 95% CI = 0.63 to 0.99). Unintentional weight loss or weight gain was not associated with overall obesity-related cancer risk. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Health Research Institute |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Howard, Barbara V |
| 790 ## - Authors |
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| All authors |
Barrington W, Chlebowski RT, Figueiredo JC, Garcia DO, Hendryx M, Ho GY, Howard BV, LeBlanc ES, Luo J, Manson JE, Reding K, Rohan TE |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1093/jncics/pkz054">https://dx.doi.org/10.1093/jncics/pkz054</a> |
| Public note |
https://dx.doi.org/10.1093/jncics/pkz054 |
| 858 ## - ORCID |
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| ORCID text |
Howard, Barbara V |
| Orcid |
<a href="https://orcid.org/0000-0002-4216-7859">https://orcid.org/0000-0002-4216-7859</a> |
| Name |
https://orcid.org/0000-0002-4216-7859 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
