MARC details
| 000 -LEADER |
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| fixed length control field |
03570nam a22005177a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
230316s20232023 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1545-9683 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1177/15459683221143461 [doi] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
36575958 |
| 245 ## - TITLE STATEMENT |
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| Title |
Interpreting the CPASS Trial: Do Not Shift Motor Therapy to the Subacute Phase. |
| 251 ## - Source |
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| Source |
Neurorehabilitation & Neural Repair. 37(1):76-79, 2023 Jan. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Neurorehabil Neural Repair. 37(1):76-79, 2023 Jan. |
| 253 ## - Journal Name |
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| Journal name |
Neurorehabilitation and neural repair |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Publication date |
2023 Jan |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
ppublish |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Medline status |
MEDLINE |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
The Critical Periods After Stroke Study (CPASS, n = 72) showed that, compared to controls, an additional 20 hours of intensive upper limb therapy led to variable gains on the Action Research Arm Test depending on when therapy was started post-stroke: the subacute group (2-3 months) improved beyond the minimal clinically important difference and the acute group (0-1 month) showed smaller but statistically significant improvement, but the chronic group (6-9 months) did not demonstrate improvement that reached significance. Some have misinterpreted CPASS results to indicate that all inpatient motor therapy should be shifted to outpatient therapy delivered 2 to 3 months post-stroke. Instead, however, CPASS argues for a large dose of motor therapy delivered continuously and cumulatively during the acute and subacute phases. When interpreting trials like CPASS, one must consider the substantial dose of early usual customary care (UCC) motor therapy that all participants received. CPASS participants averaged 27.9 hours of UCC occupational therapy (OT) during the first 2 months and 9.8 hours of UCC OT during the third and fourth months post-stroke. Any recovery experienced would therefore result not just from CPASS intensive motor therapy but the combined effects of experimental therapy plus UCC. Statistical limitations also did not allow direct comparisons of the acute and subacute group outcomes in CPASS. Instead of shifting inpatient therapy hours to the subacute phase, CPASS argues for preserving inpatient UCC. We also recommend conducting multi-site dosing trials to determine whether additional intensive motor therapy delivered in the first 2 to 3 months following inpatient rehabilitation can further improve outcomes. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Occupational Therapy |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Stroke |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Stroke Rehabilitation |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Exercise Therapy/mt [Methods] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Occupational Therapy/mt [Methods] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Paresis/rh [Rehabilitation] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Recovery of Function |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Stroke Rehabilitation/mt [Methods] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Stroke/th [Therapy] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Upper Extremity |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar National Rehabilitation Network |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
#z#Geed, Shashwati |
| Institution Code |
MHRH |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Brady, Kathaleen |
| Institution Code |
MHRH |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Bregman, Barbara S |
| Institution Code |
MHRH |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Dromerick, Alexander W |
| Institution Code |
MNRN |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Edwardson, Matthew A |
| Institution Code |
MHRH |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Giannetti, Margot |
| Institution Code |
MNRN |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Mitchell, Abigail |
| Institution Code |
MHRH |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Newport, Elissa L |
| Institution Code |
MNRN |
| -- |
MHRH |
| 790 ## - Authors |
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| All authors |
Edwardson MA |
| -- |
Brady K |
| -- |
Giannetti ML |
| -- |
Geed S |
| -- |
Barth J |
| -- |
Mitchell A |
| -- |
Tan MT |
| -- |
Zhou Y |
| -- |
Bregman BS |
| -- |
Newport EL |
| -- |
Edwards DF |
| -- |
Dromerick AW |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1177/15459683221143461">https://dx.doi.org/10.1177/15459683221143461</a> |
| Public note |
https://dx.doi.org/10.1177/15459683221143461 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Journal Article |
