MARC details
| 000 -LEADER |
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| fixed length control field |
02721nam a22004337a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
230411s20232023 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
2214-2509 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1016/j.idcr.2023.e01720 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
PMC9969062 [pmc] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
S2214-2509(23)00044-6 [pii] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
36860284 |
| 245 ## - TITLE STATEMENT |
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| Title |
Recurrent herpes simplex virus encephalitis with presumptive Human Herpesvirus 6 chromosomal integration. |
| 251 ## - Source |
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| Source |
IDCases. 31:e01720, 2023. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
IDCases. 31:e01720, 2023. |
| 253 ## - Journal Name |
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| Journal name |
IDCases |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Publication date |
2023 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
epublish |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Medline status |
PubMed-not-MEDLINE |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2023-04-11 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Viral encephalitis can lead to encephalopathy, epileptic activity, focal neurological deficits, and death. Prompt recognition and a high index of clinical suspicion can lead to early initiation of appropriate management. We describe an interesting case of a 61-year-old presenting with fever and altered mental status, diagnosed with numerous episodes of viral encephalitis caused by divergent and recurrent viruses. On his initial presentation, lumbar puncture revealed lymphocytic pleocytosis and positivity for Human Herpesvirus 6 (HHV-6), and he was treated with ganciclovir. On subsequent admissions, he was diagnosed with recurrent HHV-6 encephalitis as well as Herpes Simplex Virus 1 encephalitis and treated with ganciclovir, foscarnet and acyclovir. Despite prolonged courses of treatment and resolution of symptoms, he continued to have persistently high plasma viral loads of HHV-6, consistent with probable chromosomal integration. In this report, we emphasize the clinical pearl of chromosomally integrated HHV-6 that can present in a patient with persistently high plasma viral loads of HHV-6, that are non-responsive to treatment. Individuals with chromosomally integrated HHV-6 may be more susceptible to other viral infections. Copyright © 2023 The Authors. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Franklin Square Medical Center |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Union Memorial Hospital |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Hospitalist |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Infectious Diseases |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Internal Medicine Residency |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Case Reports |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Allen, Claire |
| Institution Code |
MUMH |
| Program |
Internal Medicine Residency |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Gill, Kavneet |
| Institution Code |
MFSMC |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Haas, Christopher |
| Institution Code |
MUMH |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Rao, Shiavax |
| Institution Code |
MUMH |
| Program |
Internal Medicine Residency |
| Degree |
MD |
| Resident year |
Resident PGY 3 |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Local Authors |
Wolff, Marcos |
| Institution Code |
MFSMC |
| 790 ## - Authors |
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| All authors |
Allen C, Rao SJ, Gill K, Wolff M, Haas CJ |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1016/j.idcr.2023.e01720">https://dx.doi.org/10.1016/j.idcr.2023.e01720</a> |
| Public note |
https://dx.doi.org/10.1016/j.idcr.2023.e01720 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
