Lymphoepithelial like carcinoma of the anorectal junction, a rare entity associated with human papillomavirus rather than Epstein-Barr virus: a case report. (Record no. 11558)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02668nam a22003737a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230411s20232023 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 2523-1995 |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.21037/acr-22-53 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | acr-07-22-53 [pii] |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | PMC9929663 [pmc] |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| PMID | 36817706 |
| 245 ## - TITLE STATEMENT | |
| Title | Lymphoepithelial like carcinoma of the anorectal junction, a rare entity associated with human papillomavirus rather than Epstein-Barr virus: a case report. |
| 251 ## - Source | |
| Source | Ame Case Reports. 7:3, 2023. |
| 252 ## - Abbreviated Source | |
| Abbreviated source | AME case rep.. 7:3, 2023. |
| 253 ## - Journal Name | |
| Journal name | AME case reports |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Year | 2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Manufacturer | FY2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Publication date | 2023 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] | |
| Publication status | epublish |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] | |
| Medline status | PubMed-not-MEDLINE |
| 266 ## - Date added to catalog | |
| Date added to catalog | 2023-04-11 |
| 520 ## - SUMMARY, ETC. | |
| Abstract | Background: The anal canal is a rare site for lymphoepithelial-like carcinoma (LELC) and has only been reported in two patients. LELC is an undifferentiated malignant neoplasm with lymphoid background that has been reported at various sites like salivary glands, breast etc. however very few cases have been reported in gastrointestinal (GI) tract. |
| 520 ## - SUMMARY, ETC. | |
| Abstract | Case Description: We report the third case of a 58-year-old female who presented with a complaint of mild constipation and rectal pressure for eight months. Endoscopic ultrasound (EUS) showed a 0.8 cm nodule at the anorectal junction which was resected. Pathology showed LELC of the anorectal junction with diffuse positivity with p16 immunostaining. Polymerase chain reaction (PCR) for human papillomavirus (HPV) was positive for high-risk HPV-16, in situ hybridization (ISH) for Epstein-Barr virus (EBV)-encoded ribonucleic acid (EBER) was negative, and there was no loss of nuclear expression of mismatch repair (MMR) proteins. Patient subsequently received chemoradiation with no evidence of residual disease on restaging scans. |
| 520 ## - SUMMARY, ETC. | |
| Abstract | Conclusions: The association between LELC of anal canal and viral agents such as HPV or EBV has yet to be established; however, all three cases reported to date, including our current case, were positive for high-risk HPV-16, suggesting a possible role of HPV in tumorigenesis of LELC of the anal canal. Copyright 2023 AME Case Reports. All rights reserved. |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 656 ## - INDEX TERM--OCCUPATION | |
| Department | MedStar Georgetown University Hospital/MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION | |
| Department | Pathology Residency |
| 657 ## - INDEX TERM--FUNCTION | |
| Medline publication type | Case Reports |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Local Authors | Ali, Salima Mansoor |
| Institution Code | MGUH |
| Program | Pathology Residency |
| Degree | MBBS |
| Resident year | Resident PGY 2 |
| 790 ## - Authors | |
| All authors | Ali SM, Park BU, Kallakury B |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| DOI | <a href="https://dx.doi.org/10.21037/acr-22-53">https://dx.doi.org/10.21037/acr-22-53</a> |
| Public note | https://dx.doi.org/10.21037/acr-22-53 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Item type description | Article |
| Withdrawn status | Lost status | Damaged status | Not for loan | Collection | Home library | Current library | Date acquired | Total Checkouts | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MedStar Authors Catalog | MedStar Authors Catalog | 04/11/2023 | 04/11/2023 | 04/11/2023 | Journal Article |