MARC details
| 000 -LEADER |
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| fixed length control field |
03817nam a22005057a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
230411s20232023 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0012-3706 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
00003453-990000000-00270 [pii] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1097/DCR.0000000000002448 [doi] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
36856661 |
| 245 ## - TITLE STATEMENT |
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| Title |
Clinical and Histopathologic Features of 35 Patients Treated for Colorectal Peritoneal Metastases Who Survived 5 Years. |
| 251 ## - Source |
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| Source |
Diseases of the Colon & Rectum. 2023 Feb 28 |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Dis Colon Rectum. 2023 Feb 28 |
| 253 ## - Journal Name |
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| Journal name |
Diseases of the colon and rectum |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Publication date |
2023 Feb 28 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
aheadofprint |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Medline status |
Publisher |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2023-04-11 |
| 501 ## - WITH NOTE |
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| Local holdings |
Available online from MWHC library: 1997 - present, Available in print through MWHC library: 1999 - 2006 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: Currently, patients with a limited extent of peritoneal metastases from colon and rectal cancer are treated by cytoreductive surgery combined with perioperative chemotherapy performed at experienced centers. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: The tumor biology as revealed by lymph node status and tumor differentiation plus extent of disease as measured by the response to neoadjuvant chemotherapy, peritoneal cancer index and no visible residual disease indicated a favorable outcome. See Video Abstract at http://links.lww.com/DCR/C62. Copyright © The ASCRS 2023. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
DESIGN: This is a retrospective review of a prospective database. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
LIMITATIONS: The study was limited by the retrospective nature, by unmeasured confounders, and data from a single institution. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
MAIN OUTCOME MEASURES: The primary outcomes measured were the clinical-, histologic- and treatment-related features that had an impact on 5-year survival. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
OBJECTIVE: To study and statistically evaluate features that may impact on survival of 5 years or more. These data are used in the risk/benefit analyses performed by the multidisciplinary team. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
PATIENTS: All patients who had biopsy-proven colon or rectal peritoneal metastases treated by systemic chemotherapy, complete cytoreductive surgery and perioperative surgery. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: From 131 patients who had a complete cytoreduction, 35 patients (26.7%) were identified as 5-year survivors. Median survival was 27 months. There were 16 males. Median age was 50.5 with a range of 25 to 80. By univariant analysis, an absence of lymph node involvement at the time of primary colorectal cancer resection (HR 1.899 (1.064, 3.388) p = 0.03), complete or near complete response to neoadjuvant chemotherapy (HR 0.251 (0.092, 0.684) p = 0.007), peritoneal cancer index <=17 (HR 0.509 (0.329, 0.788) p = 0.002), complete visible resection of disease indicated by completeness of cytoreduction score of 0 (HR 0.412 (0.224, 0.756) p = 0.004) and well-differentiated tumor (HR 0.34 (0.157, 0.737) p = 0.006) were significantly associated with 5 years or greater survival. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
SETTINGS: Single institution study at an academic center. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Health Research Institute |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
Washington Cancer Institute |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
MedStar General Surgery Residency |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
MedStar Georgetown University Hospital/MedStar Washington Hospital Center |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Desale, Sameer |
| Institution Code |
MHRI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Ghabra, Shadin |
| Institution Code |
MGUH |
| Program |
MedStar General Surgery Residency |
| Degree |
MBBS |
| Resident year |
Research |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Sugarbaker, Paul H |
| Institution Code |
WCI |
| 790 ## - Authors |
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| All authors |
Ghabra S, Desale S, Sugarbaker PH |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1097/DCR.0000000000002448">https://dx.doi.org/10.1097/DCR.0000000000002448</a> |
| Public note |
https://dx.doi.org/10.1097/DCR.0000000000002448 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
