Uranium quantification in semen by inductively coupled plasma mass spectrometry. (Record no. 12066)

MARC details
000 -LEADER
fixed length control field 02293nam a22003017a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 140403s20132013 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0946-672X
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 22944582
245 ## - TITLE STATEMENT
Title Uranium quantification in semen by inductively coupled plasma mass spectrometry.
251 ## - Source
Source J Trace Elem Med Biol. 2013 Jan;27(1):2-6. Epub 2012 Sep 1.
253 ## - Journal Name
Journal name Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
266 ## - Date added to catalog
Date added to catalog 2014-04-04
520 ## - SUMMARY, ETC.
Abstract In this study we report uranium analysis for human semen samples. Uranium quantification was performed by inductively coupled plasma mass spectrometry. No additives, such as chymotrypsin or bovine serum albumin, were used for semen liquefaction, as they showed significant uranium content. For method validation we spiked 2g aliquots of pooled control semen at three different levels of uranium: low at 5 pg/g, medium at 50 pg/g, and high at 1000 pg/g. The detection limit was determined to be 0.8 pg/g uranium in human semen. The data reproduced within 1.4-7% RSD and spike recoveries were 97-100%. The uranium level of the unspiked, pooled control semen was 2.9 pg/g of semen (n=10). In addition six semen samples from a cohort of Veterans exposed to depleted uranium (DU) in the 1991 Gulf War were analyzed with no knowledge of their exposure history. Uranium levels in the Veterans' semen samples ranged from undetectable (<0.8 pg/g) to 3350 pg/g. This wide concentration range for uranium in semen is consistent with known differences in current DU body burdens in these individuals, some of whom have retained embedded DU fragments.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Mass Spectrometry/mt [Methods]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Semen/ch [Chemistry]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Uranium/an [Analysis]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Medicine/Internal Medicine
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Guandalini, Gustavo
790 ## - Authors
All authors Anderson L, Centeno JA, Ejnik JW, Guandalini G, Hoover D, McDiarmid MA, Squibb K, Todorov TI, Xu H
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="http://dx.doi.org/10.1016/j.jtemb.2012.07.004">http://dx.doi.org/10.1016/j.jtemb.2012.07.004</a>
Public note http://dx.doi.org/10.1016/j.jtemb.2012.07.004
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Journal article
Holdings
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          MedStar Authors Catalog MedStar Authors Catalog 04/04/2014 1 22944582 09/26/2017 09/26/2017 04/04/2014 Journal Article

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