MARC details
| 000 -LEADER |
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| fixed length control field |
03060nam a22004337a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
130224s20132013 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0269-2813 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
23786213 |
| 245 ## - TITLE STATEMENT |
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| Title |
Meta-analysis: vitamin D and non-alcoholic fatty liver disease. |
| 251 ## - Source |
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| Source |
Alimentary Pharmacology & Therapeutics. 38(3):246-54, 2013 Aug. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Aliment Pharmacol Ther. 38(3):246-54, 2013 Aug. |
| 253 ## - Journal Name |
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| Journal name |
Alimentary pharmacology & therapeutics |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2014-02-24 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
AIM: To review systematically the association between vitamin D levels, measured as serum 25-hydroxy vitamin D [25(OH)D], and NAFLD. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent condition. Emerging evidence suggests that vitamin D may play a role in the pathogenesis of NAFLD. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: NAFLD patients have decreased serum 25(OH)D concentrations, suggesting that vitamin D may play a role in the development of NAFLD. The directionality of this association cannot be determined from cross-sectional studies. Demonstration of a causal role of hypovitaminosis D in NAFLD development in future studies could have important therapeutic implications. 2013 John Wiley & Sons Ltd. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: We used PubMed and EMBASE databases to identify all studies that assessed the association between vitamin D and NAFLD up until 22 April 2013, without language restrictions. We included studies that compared vitamin D levels between NAFLD cases and controls and also those that compared the odds of vitamin D deficiency by NAFLD status. Pooled standardised differences and odds ratios were calculated using an inverse variance method. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: Seventeen cross-sectional and case-control studies have evaluated the association between vitamin D and NAFLD. NAFLD was diagnosed using biopsy (4 studies), ultrasound or CT (10 studies) and liver enzymes (3 studies). Nine studies provided data for a quantitative meta-analysis. Compared to controls, NAFLD patients had 0.36 ng/mL (95% CI: 0.32, 0.40 ng/mL) lower levels of 25(OH)D and were 1.26 times more likely to be vitamin D deficient (OR 1.26, 95% CI: 1.17, 1.35). |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Fatty Liver/et [Etiology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Vitamin D Deficiency/co [Complications] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Vitamin D/bl [Blood] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Case-Control Studies |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Cross-Sectional Studies |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Fatty Liver/bl [Blood] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Vitamin D Deficiency/bl [Blood] |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Medicine/General Internal Medicine |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Meta-Analysis |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Agrawal, N |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Eliades, Myrto |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Spyrou, Elias |
| 790 ## - Authors |
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| All authors |
Agrawal N, Brancati FL, Clark JM, Eliades M, Guallar E, Hernaez R, Koteish AA, Lazo M, Potter JJ, Spyrou E |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="http://dx.doi.org/10.1111/apt.12377">http://dx.doi.org/10.1111/apt.12377</a> |
| Public note |
http://dx.doi.org/10.1111/apt.12377 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Journal article |
