MARC details
| 000 -LEADER |
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| fixed length control field |
02938nam a22004337a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
140821s20142014 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1742-5247 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
24533457 |
| 245 ## - TITLE STATEMENT |
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| Title |
Current application and bioavailability of drug-eluting stents. [Review] |
| 251 ## - Source |
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| Source |
Expert Opinion on Drug Delivery. 11(5):689-709, 2014 May. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Expert Opin Drug Deliv. 11(5):689-709, 2014 May. |
| 253 ## - Journal Name |
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| Journal name |
Expert opinion on drug delivery |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2014-08-21 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
AREAS COVERED: Since the introduction of first-generation DES, the technology has been refined, including 140821s in the alloy, stent design, polymer, drug and drug dose. In 2014, we will usher in a third generation of DES, which will include biodegradable polymers, polymer-free DES and bioabsorbable scaffolds. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
EXPERT OPINION: In recent years, considerable progress has been made in DES development. The BMS platform set the groundwork for the development of metal scaffolds with drug-eluting capability to prevent restenosis. Importantly, extensive research has shown long-term safety and efficacy of the newer generation DES. Available data suggest that DES can be safely and effectively used to treat a complex subset of patients and lesions, including patients presenting with acute myocardial infarction, lesions in saphenous vein grafts, chronic total occlusions, multivessel disease, small vessels, long lesions and bifurcations. One of the safety targets is to eliminate stent thrombosis. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
INTRODUCTION: Drug-eluting stents (DES) were developed to reduce the restenosis rate of bare metal stents (BMS) and comprises three main components: i) a metallic scaffold; ii) an antiproliferative drug to reduce or abolish the formation of the neointima; and iii) the polymer, which both enables and controls drug elution into the vessel wall. Over the years, growing evidence has been reported on the safety and efficacy for different indications of DES. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Coronary Restenosis/pc [Prevention & Control] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Drug-Eluting Stents |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Immunosuppressive Agents/pk [Pharmacokinetics] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Percutaneous Coronary Intervention/mt [Methods] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Biological Availability |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humans |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Heart & Vascular Institute |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Review |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Baker, Nevin C |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Escarcega, Ricardo O |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Lipinski, Michael J |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Magalhaes, Marco A |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Minha, Sa'ar |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Omar, Al-Fazir |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Torguson, Rebecca |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Waksman, Ron |
| 790 ## - Authors |
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| All authors |
Baker NC, Escarcega RO, Lipinski MJ, Magalhaes MA, Minha S, Omar AF, Torguson R, Waksman R |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="http://dx.doi.org/10.1517/17425247.2014.888054">http://dx.doi.org/10.1517/17425247.2014.888054</a> |
| Public note |
http://dx.doi.org/10.1517/17425247.2014.888054 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Journal article |
