MARC details
| 000 -LEADER |
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| fixed length control field |
03797nam a22005657a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
160113s20142014 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0195-668X |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
24598983 |
| 245 ## - TITLE STATEMENT |
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| Title |
Acquired thrombocytopenia after transcatheter aortic valve replacement: clinical correlates and association with outcomes. |
| 251 ## - Source |
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| Source |
European Heart Journal. 35(38):2663-71, 2014 Oct 7. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Eur Heart J. 35(38):2663-71, 2014 Oct 7. |
| 253 ## - Journal Name |
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| Journal name |
European heart journal |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2016-01-13 |
| 501 ## - WITH NOTE |
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| Local holdings |
Available online from MWHC library: 1996 - present (after 1 year), Available in print through MWHC library: 1999 - 2006 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
AIMS: This study aimed to evaluate incidence and correlates for low platelet count after transcatheter aortic valve replacement (TAVR) and to determine a possible association between acquired thrombocytopenia and clinical outcomes. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: Acquired thrombocytopenia was common after TAVR and was mostly resolved at patient discharge. The severity of thrombocytopenia after TAVR could be used as an excellent, easily obtainable, marker for worse short- and long-term outcomes after the procedure.Copyright Published on behalf of the European Society of Cardiology. All rights reserved. � The Author 2014. For permissions please email: [email protected]. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS AND RESULTS: Patients undergoing TAVR from two medical centres were included in the study. They were stratified according to nadir platelet count post procedure: no/mild thrombocytopenia, >100 x 10(9)/L; moderate, 50-99 x 10(9)/L; and severe, <50 x 10(9)/L. A total of 488 patients composed of the study population (age 84.7 +/- 7.5 years). At a median time of 2 days after TAVR, 176 patients (36.1%) developed significant thrombocytopenia: 149 (30.5%) moderate; 27 patients (5.5%) severe. Upon discharge, the vast majority of patients (90.2%) had no/mild thrombocytopenia. Nadir platelet count <50 x 10(9)/L was highly specific (96.3%), and a count <150 x 10(9)/L highly sensitive (91.2%), for predicting 30-day death (C-statistic 0.76). Patients with severe acquired thrombocytopenia had a significantly higher mortality rate at 1 year (66.7% for severe vs. 16.0% for no/mild vs. 20.1% for moderate; P < 0.001). In multivariate logistic regression, severe thrombocytopenia was independently associated with 1-year mortality (hazard ratio 3.44, CI: 1.02-11.6; P = 0.046). |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Aortic Valve Stenosis/su [Surgery] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Thrombocytopenia/et [Etiology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Transcatheter Aortic Valve Replacement/ae [Adverse Effects] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Aged, 80 and over |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Female |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Length of Stay |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Male |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Platelet Count |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Treatment Outcome |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Heart & Vascular Institute |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Multicenter Study |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Badr, Salem |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Barbash, Israel M |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Ben-Dor, Itsik |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Chen, Fang |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Dvir, Danny |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Fields, Jessica N |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Loh, Joshua P |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Minha, Sa'ar |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Okubagzi, Petros |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Pendyala, Lakshmana K |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Pichard, Augusto D |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Satler, Lowell F |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Torguson, Rebecca |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Waksman, Ron |
| 790 ## - Authors |
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| All authors |
Badr S, Barbash IM, Ben-Dor I, Chen F, Dvir D, Fields JN, Genereux P, Hahn RT, Kirtane AJ, Kodali S, Leon MB, Loh JP, Minha S, Okubagzi PG, Pendyala LK, Pichard AD, Satler LF, Smith C, Torguson R, Waksman R, Williams M, Xu K |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="http://dx.doi.org/10.1093/eurheartj/ehu082">http://dx.doi.org/10.1093/eurheartj/ehu082</a> |
| Public note |
http://dx.doi.org/10.1093/eurheartj/ehu082 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Journal article |
