Subclinical leaflet thrombosis and antithrombotic therapy post-TAVI: An LRT substudy. (Record no. 124)

MARC details
000 -LEADER
fixed length control field 03714nam a22005297a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 221213s20222022 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0167-5273
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1016/j.ijcard.2022.10.134 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code S0167-5273(22)01645-X [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 36272571
245 ## - TITLE STATEMENT
Title Subclinical leaflet thrombosis and antithrombotic therapy post-TAVI: An LRT substudy.
251 ## - Source
Source International Journal of Cardiology. 2022 Oct 20
252 ## - Abbreviated Source
Abbreviated source Int J Cardiol. 2022 Oct 20
253 ## - Journal Name
Journal name International journal of cardiology
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2022
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2023
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Publication date 2022 Oct 20
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
266 ## - Date added to catalog
Date added to catalog 2022-12-13
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Subclinical leaflet thrombosis (SLT) is characterized on computed tomography (CT) imaging as hypoattenuated leaflet thickening (HALT), reduced leaflet motion (RELM), and hypoattenuation affecting motion (HAM). How antithrombotic regimen type impacts SLT remains poorly understood. We evaluated how antithrombotic regimen type impacts SLT in low-risk subjects following transcatheter aortic valve implantation (TAVI).
520 ## - SUMMARY, ETC.
Abstract CONCLUSION: This is the largest study to date that evaluated the impact of different antithrombotic regimens on SLT in low-risk TAVI patients. Oral anticoagulation was associated with significantly lower rates of SLT at 30 days compared to DAPT or SAPT, and there was no apparent benefit of DAPT over SAPT. Copyright © 2022 Elsevier B.V. All rights reserved.
520 ## - SUMMARY, ETC.
Abstract METHODS: This substudy is a post hoc analysis of the LRT 1.0 and 2.0 trials to assess SLT in subjects who underwent CT or transoesophageal echocardiogram (TOE) imaging at 30 days, stratified by antithrombotic regimen received (single antiplatelet therapy [SAPT], dual antiplatelet therapy [DAPT], or oral anticoagulation). We also utilized univariable logistic regression modelling to identify echocardiographic predictors of HALT.
520 ## - SUMMARY, ETC.
Abstract RESULTS: Rates of HALT, RELM, and HAM were all significantly lower with oral anticoagulation compared to SAPT or DAPT at 30 days (HALT: 2.6% vs 14.3% vs 17.2%, respectively, with p < 0.001; RELM: 1.8% vs 9.6% vs 13.1%, respectively, with p = 0.004; and HAM: 0.9% vs 8.5% vs 9.8%, respectively, with p = 0.011). Additionally, short-term oral anticoagulation was not associated with higher bleeding rates compared to SAPT or DAPT (0.8% vs. 1.8% vs. 3.6%, p = 0.291). The presence of HALT did not significantly impact echocardiographic haemodynamic parameters at 30 days.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Health Research Institute
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Heart & Vascular Institute
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Institution MedStar Washington Hospital Center
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Department Interventional Cardiology Fellowship
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Ali, Syed
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Asch, Federico M
Institution Code MHRI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Ben-Dor, Itsik
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Bhogal, Sukhdeep
Institution Code MWHC
Program Interventional Cardiology Fellowship
Degree MBBS
Resident year Fellow PGY 8
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Local Authors Garcia-Garcia, Hector M
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Rogers, Toby
Institution Code MHVI
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Local Authors Satler, Lowell
Institution Code MHVI
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Local Authors Shea, Corey
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Shults, Christian
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Waksman, Ron
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Weissman, Gaby
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Zhang, Cheng
Institution Code MHVI
790 ## - Authors
All authors Ali S, Asch FM, Ben-Dor I, Bhogal S, Bilfinger T, Buchbinder M, Ehsan A, Garcia-Garcia HM, Gordon P, Hanna N, Levitt R, Parikh P, Rogers T, Satler LF, Shea C, Shults CC, Waksman R, Weissman G, Wilson SR, Zhang C
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1016/j.ijcard.2022.10.134">https://dx.doi.org/10.1016/j.ijcard.2022.10.134</a>
Public note https://dx.doi.org/10.1016/j.ijcard.2022.10.134
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 12/13/2022   36272571 36272571 12/13/2022 12/13/2022 Journal Article

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