MARC details
000 -LEADER |
fixed length control field |
03714nam a22005297a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
221213s20222022 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
0167-5273 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1016/j.ijcard.2022.10.134 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
S0167-5273(22)01645-X [pii] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
36272571 |
245 ## - TITLE STATEMENT |
Title |
Subclinical leaflet thrombosis and antithrombotic therapy post-TAVI: An LRT substudy. |
251 ## - Source |
Source |
International Journal of Cardiology. 2022 Oct 20 |
252 ## - Abbreviated Source |
Abbreviated source |
Int J Cardiol. 2022 Oct 20 |
253 ## - Journal Name |
Journal name |
International journal of cardiology |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2022 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2023 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Publication date |
2022 Oct 20 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
aheadofprint |
266 ## - Date added to catalog |
Date added to catalog |
2022-12-13 |
520 ## - SUMMARY, ETC. |
Abstract |
BACKGROUND: Subclinical leaflet thrombosis (SLT) is characterized on computed tomography (CT) imaging as hypoattenuated leaflet thickening (HALT), reduced leaflet motion (RELM), and hypoattenuation affecting motion (HAM). How antithrombotic regimen type impacts SLT remains poorly understood. We evaluated how antithrombotic regimen type impacts SLT in low-risk subjects following transcatheter aortic valve implantation (TAVI). |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSION: This is the largest study to date that evaluated the impact of different antithrombotic regimens on SLT in low-risk TAVI patients. Oral anticoagulation was associated with significantly lower rates of SLT at 30 days compared to DAPT or SAPT, and there was no apparent benefit of DAPT over SAPT. Copyright © 2022 Elsevier B.V. All rights reserved. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: This substudy is a post hoc analysis of the LRT 1.0 and 2.0 trials to assess SLT in subjects who underwent CT or transoesophageal echocardiogram (TOE) imaging at 30 days, stratified by antithrombotic regimen received (single antiplatelet therapy [SAPT], dual antiplatelet therapy [DAPT], or oral anticoagulation). We also utilized univariable logistic regression modelling to identify echocardiographic predictors of HALT. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: Rates of HALT, RELM, and HAM were all significantly lower with oral anticoagulation compared to SAPT or DAPT at 30 days (HALT: 2.6% vs 14.3% vs 17.2%, respectively, with p < 0.001; RELM: 1.8% vs 9.6% vs 13.1%, respectively, with p = 0.004; and HAM: 0.9% vs 8.5% vs 9.8%, respectively, with p = 0.011). Additionally, short-term oral anticoagulation was not associated with higher bleeding rates compared to SAPT or DAPT (0.8% vs. 1.8% vs. 3.6%, p = 0.291). The presence of HALT did not significantly impact echocardiographic haemodynamic parameters at 30 days. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Health Research Institute |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Heart & Vascular Institute |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Interventional Cardiology Fellowship |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Ali, Syed |
Institution Code |
MHVI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Asch, Federico M |
Institution Code |
MHRI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Ben-Dor, Itsik |
Institution Code |
MHVI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Bhogal, Sukhdeep |
Institution Code |
MWHC |
Program |
Interventional Cardiology Fellowship |
Degree |
MBBS |
Resident year |
Fellow PGY 8 |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Garcia-Garcia, Hector M |
Institution Code |
MHVI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Rogers, Toby |
Institution Code |
MHVI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Satler, Lowell |
Institution Code |
MHVI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Shea, Corey |
Institution Code |
MHVI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Shults, Christian |
Institution Code |
MHVI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Waksman, Ron |
Institution Code |
MHVI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Weissman, Gaby |
Institution Code |
MHVI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Zhang, Cheng |
Institution Code |
MHVI |
790 ## - Authors |
All authors |
Ali S, Asch FM, Ben-Dor I, Bhogal S, Bilfinger T, Buchbinder M, Ehsan A, Garcia-Garcia HM, Gordon P, Hanna N, Levitt R, Parikh P, Rogers T, Satler LF, Shea C, Shults CC, Waksman R, Weissman G, Wilson SR, Zhang C |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1016/j.ijcard.2022.10.134">https://dx.doi.org/10.1016/j.ijcard.2022.10.134</a> |
Public note |
https://dx.doi.org/10.1016/j.ijcard.2022.10.134 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |