COVID-19 Outcomes in a US Cohort of Persons Living with HIV (PLWH). (Record no. 12580)

MARC details
000 -LEADER
fixed length control field 03360nam a22004337a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 230626s20232023 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2571-841X
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.3390/reports5040041 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code NIHMS1871544 [mid]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC10104440 [pmc]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 37063094
245 ## - TITLE STATEMENT
Title COVID-19 Outcomes in a US Cohort of Persons Living with HIV (PLWH).
251 ## - Source
Source Reports (MDPI). 5(4), 2022 Dec.
252 ## - Abbreviated Source
Abbreviated source Reports (MDPI). 5(4), 2022 Dec.
253 ## - Journal Name
Journal name Reports (MDPI)
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2022
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2023
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2022 Dec
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status PubMed-not-MEDLINE
266 ## - Date added to catalog
Date added to catalog 2023-06-26
520 ## - SUMMARY, ETC.
Abstract Reported coronavirus disease 2019 (COVID-19) outcomes in persons living with HIV (PLWH) vary across cohorts. We examined clinical characteristics and outcomes of PLWH with COVID-19 compared with a matched HIV-seronegative cohort in a mid-Atlantic US healthcare system. Multivariate logistic regression was used to explore factors associated with hospitalization and death/mechanical ventilation among PLWH. Among 281 PLWH with COVID-19, the mean age was 51.5 (SD 12.74) years, 63% were male, 86% were Black, and 87% had a HIV viral load <200 copies/mL. Overall, 47% of PLWH versus 24% (p < 0.001) of matched HIV-seronegative individuals were hospitalized. Rates of COVID-19 associated cardiovascular and thrombotic events, AKI, and infections were similar between PLWH and HIV-seronegative individuals. Overall mortality was 6% (n = 18/281) in PLWH versus 3% (n = 33/1124) HIV-seronegative, p < 0.0001. Among admitted patients, mortality was 14% (n = 18/132) for PLWH and 13% (n = 33/269) for HIV-seronegative, p = 0.75. Among PLWH, hospitalization associated with older age aOR 1.04 (95% CI 1.01, 1.06), Medicaid insurance aOR 2.61 (95% CI 1.39, 4.97) and multimorbidity aOR 2.98 (95% CI 1.72, 5.23). Death/mechanical ventilation associated with older age aOR 1.06 (95% CI 1.01, 1.11), Medicaid insurance aOR 3.6 (95% CI 1.36, 9.74), and multimorbidity aOR 4.4 (95% CI 1.55, 15.9) in adjusted analyses. PLWH were hospitalized more frequently than the HIV-seronegative group and had a higher overall mortality rate, but once hospitalized had similar mortality rates. Older age, multimorbidity and insurance status associated with more severe outcomes among PLWH suggesting the importance of targeted interventions to mitigate the effects of modifiable inequities.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Indexing Automated
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Health Research Institute
656 ## - INDEX TERM--OCCUPATION
Department Infectious Diseases Fellowship
656 ## - INDEX TERM--OCCUPATION
Department MedStar Georgetown University Hospital/MedStar Washington Hospital Center
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Desale, Sameer
Institution Code MHRI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Fernandez, Stephen
Institution Code MHRI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Huang, Xu
Institution Code MHRI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Lee, Jennifer
Institution Code MGUH
Program Infectious Diseases Fellowship
Degree MD
Resident year Alumni
790 ## - Authors
All authors Spence AB, Desale S, Lee J, Kumar P, Huang X, Cooper SE, Fernandez S, Kassaye SG
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.3390/reports5040041">https://dx.doi.org/10.3390/reports5040041</a>
Public note https://dx.doi.org/10.3390/reports5040041
858 ## - ORCID
ORCID text Huang, Xu
Orcid <a href="https://orcid.org/0000-0001-9108-5115">https://orcid.org/0000-0001-9108-5115</a>
Name https://orcid.org/0000-0001-9108-5115
858 ## - ORCID
ORCID text Fernandez, Stephen
Orcid <a href="https://orcid.org/0000-0002-5112-1844">https://orcid.org/0000-0002-5112-1844</a>
Name https://orcid.org/0000-0002-5112-1844
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 06/26/2023   37063094 37063094 06/26/2023 06/26/2023 Journal Article

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