MARC details
000 -LEADER |
fixed length control field |
03360nam a22004337a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
230626s20232023 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
2571-841X |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.3390/reports5040041 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
NIHMS1871544 [mid] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
PMC10104440 [pmc] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
37063094 |
245 ## - TITLE STATEMENT |
Title |
COVID-19 Outcomes in a US Cohort of Persons Living with HIV (PLWH). |
251 ## - Source |
Source |
Reports (MDPI). 5(4), 2022 Dec. |
252 ## - Abbreviated Source |
Abbreviated source |
Reports (MDPI). 5(4), 2022 Dec. |
253 ## - Journal Name |
Journal name |
Reports (MDPI) |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2022 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2023 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Publication date |
2022 Dec |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
ppublish |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Medline status |
PubMed-not-MEDLINE |
266 ## - Date added to catalog |
Date added to catalog |
2023-06-26 |
520 ## - SUMMARY, ETC. |
Abstract |
Reported coronavirus disease 2019 (COVID-19) outcomes in persons living with HIV (PLWH) vary across cohorts. We examined clinical characteristics and outcomes of PLWH with COVID-19 compared with a matched HIV-seronegative cohort in a mid-Atlantic US healthcare system. Multivariate logistic regression was used to explore factors associated with hospitalization and death/mechanical ventilation among PLWH. Among 281 PLWH with COVID-19, the mean age was 51.5 (SD 12.74) years, 63% were male, 86% were Black, and 87% had a HIV viral load <200 copies/mL. Overall, 47% of PLWH versus 24% (p < 0.001) of matched HIV-seronegative individuals were hospitalized. Rates of COVID-19 associated cardiovascular and thrombotic events, AKI, and infections were similar between PLWH and HIV-seronegative individuals. Overall mortality was 6% (n = 18/281) in PLWH versus 3% (n = 33/1124) HIV-seronegative, p < 0.0001. Among admitted patients, mortality was 14% (n = 18/132) for PLWH and 13% (n = 33/269) for HIV-seronegative, p = 0.75. Among PLWH, hospitalization associated with older age aOR 1.04 (95% CI 1.01, 1.06), Medicaid insurance aOR 2.61 (95% CI 1.39, 4.97) and multimorbidity aOR 2.98 (95% CI 1.72, 5.23). Death/mechanical ventilation associated with older age aOR 1.06 (95% CI 1.01, 1.11), Medicaid insurance aOR 3.6 (95% CI 1.36, 9.74), and multimorbidity aOR 4.4 (95% CI 1.55, 15.9) in adjusted analyses. PLWH were hospitalized more frequently than the HIV-seronegative group and had a higher overall mortality rate, but once hospitalized had similar mortality rates. Older age, multimorbidity and insurance status associated with more severe outcomes among PLWH suggesting the importance of targeted interventions to mitigate the effects of modifiable inequities. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Indexing |
Automated |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Health Research Institute |
656 ## - INDEX TERM--OCCUPATION |
Department |
Infectious Diseases Fellowship |
656 ## - INDEX TERM--OCCUPATION |
Department |
MedStar Georgetown University Hospital/MedStar Washington Hospital Center |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Desale, Sameer |
Institution Code |
MHRI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Fernandez, Stephen |
Institution Code |
MHRI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Huang, Xu |
Institution Code |
MHRI |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Lee, Jennifer |
Institution Code |
MGUH |
Program |
Infectious Diseases Fellowship |
Degree |
MD |
Resident year |
Alumni |
790 ## - Authors |
All authors |
Spence AB, Desale S, Lee J, Kumar P, Huang X, Cooper SE, Fernandez S, Kassaye SG |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.3390/reports5040041">https://dx.doi.org/10.3390/reports5040041</a> |
Public note |
https://dx.doi.org/10.3390/reports5040041 |
858 ## - ORCID |
ORCID text |
Huang, Xu |
Orcid |
<a href="https://orcid.org/0000-0001-9108-5115">https://orcid.org/0000-0001-9108-5115</a> |
Name |
https://orcid.org/0000-0001-9108-5115 |
858 ## - ORCID |
ORCID text |
Fernandez, Stephen |
Orcid |
<a href="https://orcid.org/0000-0002-5112-1844">https://orcid.org/0000-0002-5112-1844</a> |
Name |
https://orcid.org/0000-0002-5112-1844 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |