Development and validation of a mortality risk-adjustment model for patients hospitalized for exacerbations of chronic obstructive pulmonary disease. (Record no. 1278)

MARC details
000 -LEADER
fixed length control field 03626nam a22005297a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 130912s20132013 xxu||||| |||| 00| 0 eng dOvid Technologies
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0025-7079
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 23604015
245 ## - TITLE STATEMENT
Title Development and validation of a mortality risk-adjustment model for patients hospitalized for exacerbations of chronic obstructive pulmonary disease.
251 ## - Source
Source Medical Care. 51(7):597-605, 2013 Jul.
252 ## - Abbreviated Source
Abbreviated source Med Care. 51(7):597-605, 2013 Jul.
253 ## - Journal Name
Journal name Medical care
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2013
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2014
266 ## - Date added to catalog
Date added to catalog 2013-09-17
501 ## - WITH NOTE
Local holdings Available online from MWHC library: 1996 - present
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a leading cause of hospitalization and death. We sought to develop and validate a mortality risk-adjustment model to enhance hospital performance measurement and to support comparative effectiveness research.
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: A mortality prediction model combining clinical and administrative data that can be obtained from electronic health records demonstrated good discrimination among patients hospitalized for AECOPD. The addition of admission vital signs and laboratory results enhanced clinical validity and could be applied to future comparative effectiveness research and hospital profiling efforts.
520 ## - SUMMARY, ETC.
Abstract METHODS: Using a derivation cohort of 69,299 AECOPD admissions in 2005-2006 across 172 hospitals, we developed a logistic regression model with age, sex, laboratory results, vital signs, and secondary diagnosis-based comorbidities as covariates. We converted the model coefficients into a score system and validated it using 33,327 admissions from 2007. We used the c-statistic to assess model fit.
520 ## - SUMMARY, ETC.
Abstract RESULTS: In the derivation and validation cohorts, the median (interquartile range) age was 72 (range, 63-79) versus 71 (range, 62-79) years; 45.6% versus 45.9% were male; and in-hospital mortality rates were 3.2% versus 2.9%, respectively. The predicted probability of deaths for individuals ranged from 0.004 to 0.942 versus 0.001 to 0.933, respectively. The relative contribution of variables to the predictive ability of the derivation model was age (18.3%), admission laboratory results (39.9%), vital signs (14.7%), altered mental status (7.1%), and comorbidities (19.9%). The model c-statistic was 0.83 (95% CI: 0.82, 0.84) versus 0.84 (95% CI: 0.83, 0.85), respectively, with good calibration for both cohorts.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Hospital Mortality
9 (RLIN) 448
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Hospitalization
9 (RLIN) 449
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Pulmonary Disease, Chronic Obstructive/mo [Mortality]
9 (RLIN) 450
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Pulmonary Disease, Chronic Obstructive/pp [Physiopathology]
9 (RLIN) 451
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Risk Adjustment
9 (RLIN) 452
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aged, 80 and over
9 (RLIN) 36
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aged
9 (RLIN) 2
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Confidence Intervals
9 (RLIN) 453
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Electronic Health Records
9 (RLIN) 234
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
9 (RLIN) 7
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
9 (RLIN) 11
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
9 (RLIN) 14
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Middle Aged
9 (RLIN) 15
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Models, Statistical
9 (RLIN) 454
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element New England/ep [Epidemiology]
9 (RLIN) 455
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Odds Ratio
9 (RLIN) 456
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Medicine/Pulmonary-Critical Care
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
657 ## - INDEX TERM--FUNCTION
Medline publication type Validation Studies
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Shorr, Andrew F
9 (RLIN) 447
790 ## - Authors
All authors Hyde L, Johannes RS, Lindenauer PK, Shorr AF, Sun X, Tabak YP
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="http://dx.doi.org/10.1097/MLR.0b013e3182901982">http://dx.doi.org/10.1097/MLR.0b013e3182901982</a>
Public note http://dx.doi.org/10.1097/MLR.0b013e3182901982
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Source of classification or shelving scheme Other/Generic Classification Scheme
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 09/17/2013   23604015 23604015 09/17/2013 09/17/2013 Journal Article

Powered by Koha