Live birth associated with peak serum estradiol levels in letrozole intrauterine insemination cycles. (Record no. 12839)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 04350nam a22006737a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 230316s20232023 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0015-0282 |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.fertnstert.2023.01.003 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER | |
| Standard number or code | S0015-0282(23)00006-7 [pii] |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| PMID | 36634734 |
| 245 ## - TITLE STATEMENT | |
| Title | Live birth associated with peak serum estradiol levels in letrozole intrauterine insemination cycles. |
| 247 ## - FORMER TITLE | |
| Title | Live birth associated with peak serum estradiol concentrations in letrozole intrauterine insemination (IUI) cycles. |
| 251 ## - Source | |
| Source | Fertility & Sterility. 119(5):785-791, 2023 05. |
| 252 ## - Abbreviated Source | |
| Abbreviated source | Fertil Steril. 119(5):785-791, 2023 05. |
| 253 ## - Journal Name | |
| Journal name | Fertility and sterility |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Manufacturer | FY2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Year | 2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Publication date | 2023 05 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] | |
| Publication status | ppublish |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] | |
| Medline status | MEDLINE |
| 266 ## - Date added to catalog | |
| Date updated in catalog | 2023-07-03 |
| 267 ## - Original year | |
| Original year | 2023 |
| 268 ## - Previous citation | |
| -- | Fertility & Sterility. 2023 Jan 09 |
| 269 ## - Original dates | |
| -- | Fertil Steril. 2023 Jan 09 |
| 269 ## - Original dates | |
| Original fiscal year | FY2023 |
| 269 ## - Original dates | |
| -- | 2023 Jan 09 |
| 269 ## - Original dates | |
| -- | aheadofprint |
| 269 ## - Original dates | |
| -- | Publisher |
| 520 ## - SUMMARY, ETC. | |
| Abstract | CONCLUSION: In letrozole ovulation induction cycles followed by intrauterine insemination, lower LBR and clinical pregnancy rates were found in women with lower E2 concentrations compared with higher E2 concentrations at the 25th, 50th, and 75th percentile E2 concentration quartiles. Where possible, delaying HCG trigger until E2 concentration rises following aromatase inhibition and approaches physiologic periovulatory concentration may improve pregnancy rates with letrozole followed by intrauterine insemination. Copyright � 2023. Published by Elsevier Inc. |
| 520 ## - SUMMARY, ETC. | |
| Abstract | DESIGN: Retrospective cohort study SETTING: Large, multi-center private practice PATIENTS: A total of 2,368 OI-IUI cycles in patients treated with letrozole followed by IUI were evaluated from January 1, 2014 - July 31, 2019. |
| 520 ## - SUMMARY, ETC. | |
| Abstract | INTERVENTIONS: Ovulation induction with letrozole, followed by autologous IUI MAIN OUTCOME MEASURES: The primary outcome measure was LBR as a function of serum E2 concentration at the time of hCG administration or LH surge, adjusting for age, BMI, largest follicle diameter, and number of follicles > 14 mm. Clinical pregnancy rate as a function of E2 concentration, pregnancy rate as a function of lead follicle diameter, and pregnancy loss rates were secondary outcome variables. |
| 520 ## - SUMMARY, ETC. | |
| Abstract | OBJECTIVE: To identify whether estradiol (E2) serum concentration around the day of hCG trigger or LH surge (hCG-LH) was associated with livebirth rate (LBR) during ovulation induction (OI) or controlled ovarian hyperstimulation (COH) with letrozole followed by intrauterine insemination (IUI). |
| 520 ## - SUMMARY, ETC. | |
| Abstract | RESULTS: 2,368 cycles met inclusion criteria. Outcomes were evaluated at the 25th (E2 110 pg/ml), 50th (157 pg/ml), 75th (225 pg/ml), and 90th (319 pg/ml) percentiles. LBR ranged from 9.4% - 11.1% in the lower E2 cohorts, and 12.5%-13.5% in the higher E2 cohorts. LBR was significantly greater in the cohort of women with higher E2 concentrations in all percentile comparisons except for the 90th percentile. Mean diameter of peri-ovulatory follicle diameter >20 mm or <20 mm was not independently associated with live birth rate or clinical pregnancy rate, despite a significantly higher mean E2 level in the larger follicle group. |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | *Live Birth |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | *Luteinizing Hormone |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Chorionic Gonadotropin |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Estradiol |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Insemination |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Insemination, Artificial |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Letrozole |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Ovulation Induction |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pregnancy |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pregnancy Rate |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Retrospective Studies |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Indexing | Automated |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
| Institution | MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION | |
| Department | Obstetrics & Gynecology Residency |
| 656 ## - INDEX TERM--OCCUPATION | |
| Department | Obstetrics and Gynecology |
| 657 ## - INDEX TERM--FUNCTION | |
| Medline publication type | Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Local Authors | Devine, Kate |
| Institution Code | MWHC |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Local Authors | Kodama, Samantha |
| Institution Code | MWHC |
| Program | Obstetrics & Gynecology Residency |
| Degree | MD |
| Resident year | Resident PGY 4 |
| 790 ## - Authors | |
| All authors | New EP |
| -- | Kodama S |
| -- | Devine K |
| -- | Jahandideh S |
| -- | Imudia AN |
| -- | Plosker SM |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| DOI | <a href="https://dx.doi.org/10.1016/j.fertnstert.2023.01.003">https://dx.doi.org/10.1016/j.fertnstert.2023.01.003</a> |
| Public note | https://dx.doi.org/10.1016/j.fertnstert.2023.01.003 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Item type description | Journal Article |
No items available.