MARC details
| 000 -LEADER |
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| fixed length control field |
04411nam a22004697a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
230628s20232023 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0196-8092 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1002/lsm.23662 [doi] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
37051876 |
| 245 ## - TITLE STATEMENT |
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| Title |
Treatment of burn hypertrophic scar with fractional ablative laser-assisted drug delivery can decrease levels of hyperpigmentation. |
| 251 ## - Source |
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| Source |
Lasers in Surgery & Medicine. 2023 Apr 13 |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Lasers Surg Med. 2023 Apr 13 |
| 253 ## - Journal Name |
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| Journal name |
Lasers in surgery and medicine |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Publication date |
2023 Apr 13 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
aheadofprint |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Medline status |
Publisher |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2023-06-28 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: Laser treatments have been used to treat a variety of scar symptoms, including the appearance of scars following burn injury. One such symptom is hyperpigmentation. There are several qualitative and quantitative measures of assessing improvement in hyperpigmentation over time. The Patient and Observer Scar Assessment Scale (POSAS) and Vancouver Scar Scale (VSS) are two scales that describe characteristics of scar such as pigmentation level. These scales are limited by their qualitative nature. On the other hand, spectrophotometers provide quantitative measures of pigmentation. Prior studies have reported that laser can change scar pigmentation, but no quantitative values have been reported. The current study examines changes in scar melanin index after CO2 fractional ablative laser scar revision (FLSR) via noninvasive probe measurement in patients of various Fitzpatrick skin types (FST). |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSION: Based on Melanin index values, FLSR leads to improvements in hyperpigmentation in certain patients. Copyright � 2023 Wiley Periodicals LLC. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
MATERIALS AND METHODS: Patients with scars of various sizes and etiologies were treated with FLSR. A database was constructed including 189 patients undergoing laser treatment. From this pool, individuals were selected based on the criteria that they completed at least two laser sessions and had Melanin index measurements for both of these sessions and the pre-operative visit. This criteria resulted in 63 patients of various FST in the cohort. Melanin index, POSAS-Observer (O) and -Patient (P) pigmentation and color scores and VSS-pigmentation scores were examined over time. Demographic information (age of patient at time of first treatment, age of scar at time of first treatment, use of laser-assisted drug delivery (LADD), gender, FST, and Ethnicity) were collected from the medical record. Patients were grouped as "responder" if their Melanin index indicated decreased levels of hyperpigmentation after FLSR treatment in more than half of their total number of visits and "nonresponder" if it did not. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: The majority of patients were responders (41/63). In responder patients, measurements of Melanin index showed significantly improved levels of hyperpigmentation in hypertrophic scars after two FLSR sessions (p < 0.05). Age of patient, gender, FST, age of scar, ethnicity, or type of drug delivered by LADD did not predict responder grouping. POSAS-O and -P pigmentation/color scores showed improved scores after two FLSR sessions within the responder group. POSAS-P color scores showed improved scores after two and three FLSR sessions in the nonresponder group. VSS pigmentation scores showed improved scores after three FLSR sessions in the responder group only. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Indexing |
Automated |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
Firefighters' Burn and Surgical Research Laboratory |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Health Research Institute |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Firefighters' Burn and Surgical Research Laboratory |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Case Reports |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Carney, Bonnie C |
| Institution Code |
MHRI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Kurup, Sanjana |
| Institution Code |
MHRI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Shafy, Rahma Abd El |
| Institution Code |
MHRI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Shupp, Jeffrey W |
| Institution Code |
MHRI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Travis, Taryn |
| Institution Code |
MHRI |
| 790 ## - Authors |
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| All authors |
Carney BC, Kurup S, Shafy RAE, Shupp JW, Travis TE |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1002/lsm.23662">https://dx.doi.org/10.1002/lsm.23662</a> |
| Public note |
https://dx.doi.org/10.1002/lsm.23662 |
| 858 ## - ORCID |
|---|
| Name |
http://orcid.org/0000-0003-0200-1392 |
| ORCID text |
Kurup, Sanjana |
| Orcid |
<a href="http://orcid.org/0000-0003-0200-1392">http://orcid.org/0000-0003-0200-1392</a> |
| 858 ## - ORCID |
|---|
| Name |
http://orcid.org/0000-0003-2292-4960 |
| ORCID text |
Carney, Bonnie C |
| Orcid |
<a href="http://orcid.org/0000-0003-2292-4960">http://orcid.org/0000-0003-2292-4960</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
