Predictors of Survival in Veterans with Head and Neck Cancer Treated Surgically. (Record no. 12960)

MARC details
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fixed length control field 03115nam a22003617a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 230628s20232023 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1092-6429
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1089/lap.2023.0057 [doi]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 37001169
245 ## - TITLE STATEMENT
Title Predictors of Survival in Veterans with Head and Neck Cancer Treated Surgically.
251 ## - Source
Source Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A. 2023 Mar 31
252 ## - Abbreviated Source
Abbreviated source J Laparoendosc Adv Surg Tech A. 2023 Mar 31
253 ## - Journal Name
Journal name Journal of laparoendoscopic & advanced surgical techniques. Part A
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2023
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Manufacturer FY2023
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2023 Mar 31
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status Publisher
266 ## - Date added to catalog
Date added to catalog 2023-06-28
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Local holdings Available online through MWHC library: 2000 - 2010, Available in print through MWHC library:1999-2007
520 ## - SUMMARY, ETC.
Abstract Background: Squamous cell carcinoma (SCC) accounts for 90% of all head and neck cancers. In veterans, the prevalence of head and neck SCC is nearly twice as high compared with the civilian population. Neck dissection plays an important role in the treatment algorithm for patients with head and neck SCC. The aim of this manuscript was to investigate predictors of survival in patients with head and neck SCC who underwent curative treatment. Methods: Patients with head and neck SCC who underwent treatment with curative intent were included in this study. Data collected included clinical-demographic characteristics, tumor characteristics, and outcome. The primary endpoint was 3-year overall survival (OS), and the secondary endpoints were disease recurrence and distant metastases. Results: A total of 149 patients met inclusion criteria, and most patients were treated with surgery plus adjuvant chemoradiation (52%). The 3-year OS for the entire cohort was 55.7%. There was no statistically significant difference in mortality when comparing the various treatment types. Black patients (hazard ratio [HR] = 1.70, P = .023) and other non-white patients (HR = 3.88, P = .027) had worse 3-year OS compared with white patients. Advanced tumor classification (T4a) was also associated with worse 3-year OS (HR = 3.088, P = .003) and increased risk of cancer recurrence or distant metastases (HR = 3.34, P = .013). Conclusions: Risk factors linked to poor survival among this cohort of veterans with head and neck SCC included non-white race and advanced tumor classification. Neck dissection remains an integral aspect of the treatment algorithm for SCC of the head and neck and can provide regional control of malignant disease.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
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Indexing Automated
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Department MedStar Georgetown University Hospital/MedStar Washington Hospital Center
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Department Otolaryngology Residency
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Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Wu, Eric
Institution Code MGUH
Program Otolaryngology Residency
Degree MD
Resident year Resident PGY 5
790 ## - Authors
All authors Brody L, Jackson JM, Maxwell JH, Wu EL
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1089/lap.2023.0057">https://dx.doi.org/10.1089/lap.2023.0057</a>
Public note https://dx.doi.org/10.1089/lap.2023.0057
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 06/28/2023   37001169 37001169 06/28/2023 06/28/2023 Journal Article

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