Cerebrovascular Complications of COVID-19 on Venovenous Extracorporeal Membrane Oxygenation. (Record no. 13111)

MARC details
000 -LEADER
fixed length control field 04332nam a22006977a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 230628s20232023 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0090-3493
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 00003246-990000000-00131 [pii]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1097/CCM.0000000000005861 [doi]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 37010526
245 ## - TITLE STATEMENT
Title Cerebrovascular Complications of COVID-19 on Venovenous Extracorporeal Membrane Oxygenation.
251 ## - Source
Source Critical Care Medicine. 51(8):1043-1053, 2023 Aug 01.
252 ## - Abbreviated Source
Abbreviated source Crit Care Med. 51(8):1043-1053, 2023 Aug 01.
253 ## - Journal Name
Journal name Critical care medicine
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2023
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2023 Aug 01
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status MEDLINE
267 ## - Original year
Original year 2023
268 ## - Previous citation
Original Source Critical Care Medicine. 2023 Apr 03
268 ## - Previous citation
-- 2023-06-28
268 ## - Previous citation
Original abbreviated source Crit Care Med. 2023 Apr 03
268 ## - Previous citation
Original publication status aheadofprint
268 ## - Previous citation
Original Medline status Publisher
269 ## - Original dates
Original fiscal year FY2023
501 ## - WITH NOTE
Local holdings Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: Our study highlights the association of obesity and pre-ECMO vasopressor use with the development of stroke in COVID-19 patients on venovenous ECMO. Also, the importance of relative decrease in Paco2 and moderate hyperoxia within 48 hours after ECMO initiation were additional risk factors. Copyright 2023 by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved.
520 ## - SUMMARY, ETC.
Abstract DESIGN: We analyzed prospectively collected observational data, using univariable and multivariable survival modeling to identify risk factors for stroke. Cox proportional hazards and Fine-Gray models were used, with death and discharge treated as competing risks.
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Abstract INTERVENTIONS: None.
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Abstract MEASUREMENTS AND MAIN RESULTS: Five hundred ninety-five patients (median age [interquartile range], 51 yr [42-59 yr]; male: 70.8%) had venovenous ECMO support. Forty-three patients (7.2%) suffered strokes, 83.7% of which were hemorrhagic. In multivariable survival analysis, obesity (adjusted hazard ratio [aHR], 2.19; 95% CI, 1.05-4.59) and use of vasopressors before ECMO (aHR, 2.37; 95% CI, 1.08-5.22) were associated with an increased risk of stroke. Forty-eight-hour post-ECMO Paco2-pre-ECMO Paco2/pre-ECMO Paco2 (relative DELTAPaco2) of negative 26% and 48-hour post-ECMO Pao2-pre-ECMO Pao2/pre-ECMO Pao2 (relative DELTAPao2) of positive 24% at 48 hours of ECMO initiation were observed in stroke patients in comparison to relative DELTAPaco2 of negative 17% and relative DELTAPao2 of positive 7% in the nonstroke group. Patients with acute stroke had a 79% in-hospital mortality compared with 45% mortality for stroke-free patients.
520 ## - SUMMARY, ETC.
Abstract OBJECTIVES: Evidence of cerebrovascular complications in COVID-19 requiring venovenous extracorporeal membrane oxygenation (ECMO) is limited. Our study aims to characterize the prevalence and risk factors of stroke secondary to COVID-19 in patients on venovenous ECMO.
520 ## - SUMMARY, ETC.
Abstract PATIENTS: Adult COVID-19 patients who were supported by venovenous ECMO.
520 ## - SUMMARY, ETC.
Abstract SETTING: Three hundred eighty institutions in 53 countries in the COVID-19 Critical Care Consortium (COVID Critical) registry.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *COVID-19
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Extracorporeal Membrane Oxygenation
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Topical term or geographic name entry element *Stroke
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Adult
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Carbon Dioxide
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element COVID-19/co [Complications]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element COVID-19/ep [Epidemiology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element COVID-19/th [Therapy]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Extracorporeal Membrane Oxygenation/ae [Adverse Effects]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Middle Aged
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Obesity
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Stroke/ep [Epidemiology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Stroke/et [Etiology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Indexing Automated
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Surgery/Surgical Critical Care
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Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Zaaqoq, Akram M
Institution Code MWHC
790 ## - Authors
All authors Cho SM, Fanning JP, Fraser JF, Griffee MJ, Heinsar S, Jacobs JP, Kelly TL, Li Bassi G, Lorusso R, Mariani S, Peek GJ, Suen JY, White N, Zaaqoq AM
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1097/CCM.0000000000005861">https://dx.doi.org/10.1097/CCM.0000000000005861</a>
Public note https://dx.doi.org/10.1097/CCM.0000000000005861
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 06/28/2023   37010526 37010526 06/28/2023 06/28/2023 Journal Article

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