Coronary microvascular dysfunction and cancer therapy-related cardiovascular toxicity. (Record no. 14419)

MARC details
000 -LEADER
fixed length control field 03916nam a22005657a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 240807s20242024 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1878-0938
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code S1553-8389(24)00459-7 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 38789343
245 ## - TITLE STATEMENT
Title Coronary microvascular dysfunction and cancer therapy-related cardiovascular toxicity.
251 ## - Source
Source Cardiovascular Revascularization Medicine. 2024 May 07
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Abbreviated source Cardiovasc Revasc Med. 2024 May 07
253 ## - Journal Name
Journal name Cardiovascular revascularization medicine : including molecular interventions
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2024
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Manufacturer FY2024
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Publication date 2024 May 07
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status Publisher
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Date added to catalog 2024-08-07
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Date Medline record created 2024/05/24 21:55
501 ## - WITH NOTE
Local holdings Available in print through MWHC library: 2002 - present
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Abstract BACKGROUND: Coronary microvascular dysfunction (CMD) has been implicated as a potential mechanism in the pathophysiology of different clinical presentations, including ischemia and no obstructive coronary artery disease (INOCA), myocardial infarction and nonobstructive coronary arteries (MINOCA), stress cardiomyopathy, heart failure, and myocarditis. There are limited data about the role of CMD in cancer therapy-related cardiovascular toxicities.
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Abstract CASE PRESENTATIONS: Four women with a diagnosis of active cancer receiving treatment who developed subsequent MINOCA or INOCA presented for cardiac catheterization. Upon coronary angiography showing no obstructive coronary arteries, coronary function testing was performed to evaluate for CMD.
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Abstract CONCLUSIONS: CMD may play a role in cardiovascular toxicities. Further coronary physiology studies are needed to understand the mechanisms of cancer therapy-related cardiovascular toxicity and CMD, as well as optimal preventive and treatment options. Copyright © 2024. Published by Elsevier Inc.
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Abstract METHODS: Coronary physiology was assessed measuring non-hyperemic (resting full-cycle ratio [RFR]) and hyperemic (fractional flow reserve [FFR]) indices using a physiologic pressure wire. The wire also measured coronary flow reserve (CFR), index of microcirculatory resistance (IMR), and RFR using thermodilution technology. CMD was confirmed if the CFR was <2.5 and the IMR was >25.
520 ## - SUMMARY, ETC.
Abstract RESULTS: Among 4 patients with diagnosis of active cancer presenting with chest pain, there was no evidence of obstructive coronary artery disease, leading to separate diagnoses of INOCA, MINOCA, stress cardiomyopathy, and myocarditis. We found CMD in 2 patients (1 with INOCA and 1 with immune checkpoint inhibitor-related myocarditis).
546 ## - LANGUAGE NOTE
Language note English
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Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
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Indexing Automated
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Institution MedStar Heart & Vascular Institute
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Institution MedStar Washington Hospital Center
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Department Advanced Cardiac Catheterization Research Fellowship
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Department Cardiac Oncology Fellowship
657 ## - INDEX TERM--FUNCTION
Medline publication type Case Reports
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Local Authors Abusnina, Waiel
Institution Code MWHC
Program Advanced Cardiac Catheterization Research Fellowship
Degree MBBCh
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Local Authors Barac, Ana
Institution Code MHVI
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Local Authors Ben-Dor, Itsik
Institution Code MHVI
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Local Authors Bhogal, Sukhdeep
Institution Code MHVI
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Local Authors Case, Brian C
Institution Code MHVI
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Local Authors Chaturvedi, Abhishek
Institution Code MWHC
Program Advanced Cardiac Catheterization Research Fellowship
Degree MBBS
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Local Authors Chitturi, Kalyan
Institution Code MWHC
Program Advanced Cardiac Catheterization Research Fellowship
Degree DO
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Local Authors Hashim, Hayder
Institution Code MHVI
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Local Authors Kassaian, Seyed Ebrahim
Institution Code MWHC
Program Cardiac Oncology Fellowship
Degree MD
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Local Authors Merdler, Ilan
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Waksman, Ron
Institution Code MHVI
790 ## - Authors
All authors Chitturi KR, Bhogal S, Kassaian SE, Merdler I, Abusnina W, Chaturvedi A, Ben-Dor I, Waksman R, Case BC, Barac A, Hashim HD
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DOI <a href="https://dx.doi.org/10.1016/j.carrev.2024.05.001">https://dx.doi.org/10.1016/j.carrev.2024.05.001</a>
Public note https://dx.doi.org/10.1016/j.carrev.2024.05.001
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Barcode Date last seen Price effective from Koha item type
              08/07/2024   38789343 08/07/2024 08/07/2024 Journal Article

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