Impact of Significant Hemoglobin Drop Without Bleeding in Patients Undergoing Transcatheter Aortic Valve Replacement. (Record no. 14526)

MARC details
000 -LEADER
fixed length control field 04879nam a22007697a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 240807s20242024 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2047-9980
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC11255624 [pmc]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 38818933
245 ## - TITLE STATEMENT
Title Impact of Significant Hemoglobin Drop Without Bleeding in Patients Undergoing Transcatheter Aortic Valve Replacement.
251 ## - Source
Source Journal of the American Heart Association. 13(11):e032291, 2024 Jun 04.
252 ## - Abbreviated Source
Abbreviated source J Am Heart Assoc. 13(11):e032291, 2024 Jun 04.
253 ## - Journal Name
Journal name Journal of the American Heart Association
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2024
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2024
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2024 Jun 04
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status MEDLINE
266 ## - Date added to catalog
Date added to catalog 2024-08-07
266 ## - Date added to catalog
Date Medline record created 2024/05/31 07:13
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Hemoglobin (Hgb) drop without bleeding is common among patients undergoing transcatheter aortic valve replacement; however, the clinical implications of significant Hgb drop have not been fully evaluated.
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: Hgb drop without bleeding is common among patients undergoing transcatheter aortic valve replacement and may represent a higher risk of periprocedural death. Blood transfusion increases short- and midterm mortality risk in patients with and without bleeding, supporting a restrictive transfusion strategy.
520 ## - SUMMARY, ETC.
Abstract METHODS AND RESULTS: Consecutive patients undergoing transcatheter aortic valve replacement at our institution from 2011 to 2021 were retrospectively reviewed. Three groups were assessed: no Hgb drop and no bleed (NoD-NoB [reference group]), Hgb drop with bleed, and Hgb drop and no bleed (D-NoB). Hgb drop was defined as >=3 g/dL decrease from pre- to post-transcatheter aortic valve replacement. Outcomes of interest were in-hospital death and 1-year all-cause mortality. A total of 1851 cases with complete Hgb data were included: NoD-NoB: n=1579 (85.3%); D-NoB: n=49 (2.6%); Hgb drop with bleed: n=223 (12.6%). Compared with NoD-NoB, the D-NoB group was older (81.1 versus 78.9 years of age) with higher preprocedure Hgb (12.9 versus 11.7 g/dL). In-hospital death rate was higher among patients with D-NoB versus NoD-NoB (4.5% versus 0.8%, P<0.001) and similar to Hgb drop with bleed (4.5% versus 4.1%, P=0.999). Predictors of in-hospital death were D-NoB (odds ratio [OR], 3.45 [95% CI, 1.32-8.69]) and transfusion (OR, 10.6 [95% CI, 4.25-28.2]). Landmark survival analysis found that D-NoB experienced 1-year mortality rate comparable to NoD-NoB, whereas Hgb drop with bleed had higher midterm mortality (hazard ratio [HR], 3.2 [95% CI, 1.83-5.73]), and transfusion continued to impact mortality (HR, 2.5 [95% CI, 1.79-3.63]).
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Aortic Valve Stenosis
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Hemoglobins
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Hospital Mortality
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Transcatheter Aortic Valve Replacement
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aged
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aged, 80 and over
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aortic Valve Stenosis/mo [Mortality]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aortic Valve Stenosis/su [Surgery]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Hemoglobins/an [Analysis]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Hemoglobins/me [Metabolism]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Retrospective Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Risk Assessment/mt [Methods]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Risk Factors
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Transcatheter Aortic Valve Replacement/ae [Adverse Effects]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Transcatheter Aortic Valve Replacement/mo [Mortality]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Treatment Outcome
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Indexing Curated
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Heart & Vascular Institute
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Advanced Cardiac Catheterization Research Fellowship
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Ben-Dor, Itsik
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Cellamare, Matteo
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Garcia-Garcia, Hector M
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Merdler, Ilan
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Reddy, Pavan
Institution Code MWHC
Program Advanced Cardiac Catheterization Research Fellowship
Degree MD
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Rogers, Toby
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Satler, Lowell F
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Waksman, Ron
Institution Code MHVI
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Zhang, Cheng
Institution Code MHVI
790 ## - Authors
All authors Reddy P, Merdler I, Zhang C, Cellamare M, Ben-Dor I, Satler LF, Rogers T, Garcia-Garcia HM, Waksman R
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1161/JAHA.123.032291">https://dx.doi.org/10.1161/JAHA.123.032291</a>
Public note https://dx.doi.org/10.1161/JAHA.123.032291
858 ## - ORCID
ORCID text Garcia-Garcia, Hector M
Orcid <a href="https://orcid.org/0000-0001-5100-0471">https://orcid.org/0000-0001-5100-0471</a>
Name https://orcid.org/0000-0001-5100-0471
858 ## - ORCID
ORCID text Reddy, Pavan
Orcid <a href="https://orcid.org/0000-0001-8913-7430">https://orcid.org/0000-0001-8913-7430</a>
Name https://orcid.org/0000-0001-8913-7430
858 ## - ORCID
ORCID text Rogers, Toby
Orcid <a href="https://orcid.org/0000-0002-6043-3137">https://orcid.org/0000-0002-6043-3137</a>
Name https://orcid.org/0000-0002-6043-3137
858 ## - ORCID
ORCID text Satler, Lowell F
Orcid <a href="https://orcid.org/0000-0001-6446-2683">https://orcid.org/0000-0001-6446-2683</a>
Name https://orcid.org/0000-0001-6446-2683
858 ## - ORCID
ORCID text Waksman, Ron
Orcid <a href="https://orcid.org/0000-0002-4063-9226">https://orcid.org/0000-0002-4063-9226</a>
Name https://orcid.org/0000-0002-4063-9226
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Barcode Date last seen Price effective from Koha item type
              08/07/2024   38818933 08/07/2024 08/07/2024 Journal Article

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