MARC details
000 -LEADER |
fixed length control field |
02551nam a22004577a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
160908s20152015 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
1087-2418 |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
26761420 |
245 ## - TITLE STATEMENT |
Title |
The microbiome and its implications in intestinal transplantation. [Review] |
251 ## - Source |
Source |
Current Opinion in Organ Transplantation. 21(2):135-9, 2016 Apr. |
252 ## - Abbreviated Source |
Abbreviated source |
Curr Opin Organ Transplant. 21(2):135-9, 2016 Apr. |
253 ## - Journal Name |
Journal name |
Current opinion in organ transplantation |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2016 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2016 |
266 ## - Date added to catalog |
Date added to catalog |
2017-03-06 |
520 ## - SUMMARY, ETC. |
Abstract |
PURPOSE OF REVIEW: This article summarizes the complex interplay between the microbiota and host immune responses, and its impact on intestinal transplantation and allograft rejection. |
520 ## - SUMMARY, ETC. |
Abstract |
RECENT FINDINGS: Recent findings highlight the importance of Paneth cells as crucial producers of antimicrobial peptides that control the intestinal host-microbial interface as well as the essential role of NOD2 as a master regulator of antimicrobial host defenses. Moreover, complex interactions between innate and adaptive immune responses have been shown to critically shape host antimicrobial Th17 responses, which may be key for the pathogenesis of inflammatory bowel diseases and intestinal allograft rejection. |
520 ## - SUMMARY, ETC. |
Abstract |
SUMMARY: A growing body of evidence indicates that crosstalk between the microbiome and innate and adaptive host immunity determines alloimmune responses and outcomes in intestinal transplantation. Elaboration of this emerging field might lead to novel mechanistic insight into these complex interactions and allow for new therapeutic approaches. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Intestines/mi [Microbiology] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Intestines/tr [Transplantation] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Microbiota |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Graft Rejection |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Humans |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Intestines/im [Immunology] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Paneth Cells/mi [Microbiology] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Th17 Cells/im [Immunology] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Transplantation, Homologous |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Surgery/Transplantation |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Research Support, Non-U.S. Gov't |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Review |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Elsabbagh, Ahmed M |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Fishbein, Thomas M |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Matsumoto, Cal S |
790 ## - Authors |
All authors |
Elsabbagh AM, Fishbein TM, Kroemer A, Matsumoto CS, Zasloff M |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="http://dx.doi.org/10.1097/MOT.0000000000000278">http://dx.doi.org/10.1097/MOT.0000000000000278</a> |
Public note |
http://dx.doi.org/10.1097/MOT.0000000000000278 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |