Serial volumetric assessment of coronary fibroatheroma by optical frequency domain imaging: insights from the TROFI trial. (Record no. 2139)

MARC details
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fixed length control field 03902nam a22005777a 4500
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fixed length control field 170428s20172017 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2047-2404
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 28200140
245 ## - TITLE STATEMENT
Title Serial volumetric assessment of coronary fibroatheroma by optical frequency domain imaging: insights from the TROFI trial.
251 ## - Source
Source European heart journal cardiovascular Imaging. 19(1):92-100, 2018 01 01.
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Abbreviated source Eur Heart J Cardiovasc Imaging. 19(1):92-100, 2018 01 01.
253 ## - Journal Name
Journal name European heart journal cardiovascular Imaging
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2017
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Manufacturer FY2017
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
266 ## - Date added to catalog
Date added to catalog 2017-05-06
520 ## - SUMMARY, ETC.
Abstract Aims: Coronary lesions precursors of acute events remain elusive, since they undergo continuous changes and their temporal changes are not very well-characterized. In natural history studies, optical frequency domain imaging (OFDI) has been used only to assess fibroatheromas as a 2D structure and sometimes in a single frame fashion. We aim at describing the serial volumetric modifications of the fibrous cap (FC) of the fibroatheromas as determined by OFDI over a 6-month follow-up period.
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Abstract Conclusions: Non-culprit fibroatheromas located in the infarct related artery of patients with STEMI had a volumetric reduction of the FC after 6-month follow-up. Quantitative FC assessment was able to differentiate high-risk lesions that became ThCFAs. There was a considerable change of plaque phenotype (TCFAs or ThCFAs) over time.
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Abstract Copyright Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2017. For permissions, please email: [email protected].
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Abstract Methods and results: In 49 patients, OFDI investigation was performed following treatment of culprit lesion and at 6-month follow-up in patients with ST-segment elevation myocardial infarction (STEMI). A fully automatic volumetric quantification of FC was done in all lipid-containing frames of non-culprit lesions in the infarct related artery. These lesions were matched at baseline and 6-month follow-up. A total of 58 non-culprit lipid rich lesions (34 TCFAs and 24 thick-cap fibroatheroma [ThCFA]) were found in 34 patients at baseline. Overall, there was a FC volume decrease of 1.57 (Inter-quartile Range [IQR] -4.13 to 0.54) mm3 at 6-months. 27% of the lesions changed their phenotype over time (TCFA or ThCFA). TCFAs that became ThCFAs at follow-up had smaller mean and maximal FC as compared with lesions that remained TCFAs (P = 0.01 for both).
546 ## - LANGUAGE NOTE
Language note English
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Topical term or geographic name entry element *Coronary Artery Disease/dg [Diagnostic Imaging]
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Topical term or geographic name entry element *Plaque, Atherosclerotic/dg [Diagnostic Imaging]
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Topical term or geographic name entry element *ST Elevation Myocardial Infarction/th [Therapy]
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Topical term or geographic name entry element *Thrombectomy/mt [Methods]
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Topical term or geographic name entry element *Tomography, Optical Coherence/mt [Methods]
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Topical term or geographic name entry element Aged
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Topical term or geographic name entry element Combined Modality Therapy
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Coronary Artery Disease/th [Therapy]
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Topical term or geographic name entry element Female
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Topical term or geographic name entry element Follow-Up Studies
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Topical term or geographic name entry element Humans
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Topical term or geographic name entry element Male
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Topical term or geographic name entry element Middle Aged
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Percutaneous Coronary Intervention
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Plaque, Atherosclerotic/su [Surgery]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Prospective Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Risk Assessment
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ST Elevation Myocardial Infarction/dg [Diagnostic Imaging]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element ST Elevation Myocardial Infarction/mo [Mortality]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Survival Rate
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Topical term or geographic name entry element Time Factors
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Topical term or geographic name entry element Treatment Outcome
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Heart & Vascular Institute
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Garcia-Garcia, Hector M
790 ## - Authors
All authors Campos CM, Dijkstra J, Garcia-Garcia HM, Iqbal J, Muramatsu T, Nakatani S, Onuma Y, Serruys PW
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DOI <a href="https://dx.doi.org/10.1093/ehjci/jew338">https://dx.doi.org/10.1093/ehjci/jew338</a>
Public note https://dx.doi.org/10.1093/ehjci/jew338
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
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          MedStar Authors Catalog MedStar Authors Catalog 05/06/2017   28200140 28200140 05/06/2017 05/06/2017 Journal Article

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