MARC details
| 000 -LEADER |
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| fixed length control field |
02678nam a22003617a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
170823s20122012 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1239-9736 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
28156314 |
| 245 ## - TITLE STATEMENT |
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| Title |
Heart rate is associated with markers of fatty acid desaturation: the GOCADAN study. |
| 251 ## - Source |
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| Source |
International Journal of Circumpolar Health. 71(1):17343, 2012 Jan |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Int J Circumpolar Health. 71(1):17343, 2012 Jan |
| 253 ## - Journal Name |
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| Journal name |
International journal of circumpolar health |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2012 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2013 |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2017-08-23 |
| 501 ## - WITH NOTE |
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| Local holdings |
Available online through MWHC library: 2002 - present |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSION: Endogenous FA desaturation is associated with HR and thereby, in the case of SCD, possibly with arrhythmia and sudden death, which would at least partially explain the previously observed association between cardiovascular mortality and desaturase activity. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: Data of FA concentrations from plasma and red blood cell membranes from those >=35 years of age (n = 819) were compared to basal HR at the time of examination. Multiple linear regression with backward stepwise selection was employed to analyze the effect of the desaturase indexes on HR, after adjustment for relevant covariates. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
OBJECTIVES: To determine if heart rate (HR) is associated with desaturation indexes as HR is associated with arrhythmia and sudden death. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: The DELTA<sup>5</sup> desaturase index (DELTA<sup>5</sup>-DI) measured in serum has recently been associated with a protective role for cardiovascular disease. This index measured here in plasma and red blood cells showed a negative correlation with HR. The plasma stearoyl-CoA-desaturase (SCD) index, previously determined to be related to cardiovascular disease (CVD) mortality, on the other hand, was positively associated with HR, while the DELTA<sup>6</sup> desaturase index (DELTA<sup>6</sup>-DI) had no significant effect on HR. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
STUDY DESIGN: A community based cross-sectional study of 1214 Alaskan Inuit. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Health Research Institute |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Howard, Barbara V |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Howard, William J |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Umans, Jason G |
| 790 ## - Authors |
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| All authors |
Comuzzie A, Devereux R, Ebbesson LE, Ebbesson SE, Elizabeth Tejero M, Fabsitz R, Harris W, Howard B, Howard W, Kennish J, Laston S, Lopez-Alvarenga J, MacCluer J, Okin P, Umans J, Wenger C |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.3402/ijch.v71i0.17343">https://dx.doi.org/10.3402/ijch.v71i0.17343</a> |
| Public note |
https://dx.doi.org/10.3402/ijch.v71i0.17343 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
