Outcomes in 937 Intermediate-Risk Patients Undergoing Surgical Aortic Valve Replacement in PARTNER 2A. (Record no. 2979)

MARC details
000 -LEADER
fixed length control field 03802nam a22005297a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 180118s20182018 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0003-4975
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1016/j.athoracsur.2017.10.062 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code S0003-4975(17)31617-X [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 29253463
245 ## - TITLE STATEMENT
Title Outcomes in 937 Intermediate-Risk Patients Undergoing Surgical Aortic Valve Replacement in PARTNER 2A.
251 ## - Source
Source Annals of Thoracic Surgery. 105(5):1322-1329, 2018 05.
252 ## - Abbreviated Source
Abbreviated source Ann Thorac Surg. 105(5):1322-1329, 2018 05.
253 ## - Journal Name
Journal name The Annals of thoracic surgery
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2018
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2018
266 ## - Date added to catalog
Date added to catalog 2018-01-18
501 ## - WITH NOTE
Local holdings Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: The PARTNER-2A randomized trial compared outcomes of transfemoral transcatheter (TAVR) and surgical aortic valve replacement (SAVR) in intermediate-risk patients with severe aortic stenosis. The purpose of the current study was to perform an in-depth analysis of outcomes after SAVR in PARTNER-2A.
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: In this adjudicated prospective study, SAVR in intermediate-risk patients had excellent results at 2 years. However, there were more in-hospital strokes than expected, most likely attributable to mandatory neurologic assessment post-procedure. There was no significant structural valve deterioration during 2-year follow-up. Continued long-term surveillance remains important. Copyright (c) 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
520 ## - SUMMARY, ETC.
Abstract METHODS: From 1/2012-1/2014, 937 patients underwent SAVR at 57 centers. Mean age was 82+/-6.7 and 55% were men. Less-invasive operations were performed in 140 (15%) and concomitant procedures in 198 (21%). Major outcomes and echocardiograms were adjudicated by an independent events committee. Follow-up was 94% complete to 2 years.
520 ## - SUMMARY, ETC.
Abstract RESULTS: Operative mortality was 4.1% (n=38, STS PROM 5.2+/-2.3%), O/E 0.8, and in-hospital stroke 5.4% (n=51), twice expected. Aortic clamp and bypass times were 75+/-30 and 104+/-46 minutes. Patients having severe prosthesis-patient mismatch (n=260, 33%) had similar survival to those without (P>.9), as did those undergoing less-invasive SAVR (P=.3). Risk factors for death included cachexia (P=.004), tricuspid regurgitation (P=.01), coronary artery disease (P=.02), preoperative atrial fibrillation (P=.001), higher white cell count (P<.0001), and lower hemoglobin (P=.0002).
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Aortic Valve Stenosis/su [Surgery]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Postoperative Complications/ep [Epidemiology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Transcatheter Aortic Valve Replacement/ae [Adverse Effects]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aged
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aged, 80 and over
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aortic Valve Stenosis/mo [Mortality]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cohort Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Hospital Mortality
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Length of Stay
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Risk Factors
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Survival Rate
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Treatment Outcome
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Heart & Vascular Institute
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Corso, Paul J
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Pichard, Augusto D
790 ## - Authors
All authors Ailawadi G, Alu MC, Babaliaros VC, Bavaria JE, Blackstone EH, Corso PJ, Forcillo J, Greason KL, Hahn RT, Herrmann HC, Jaber WA, Kapadia S, Kodali SK, Leon MB, Lowry AM, Mack MJ, Makkar RR, Maniar HS, Miller DC, PARTNER Trial Investigators, Pichard AD, Rajeswaran J, Semple M, Smith CR, Suri RM, Svensson LG, Szeto WY, Thourani VH, Trento A, Williams MR
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1016/j.athoracsur.2017.10.062">https://dx.doi.org/10.1016/j.athoracsur.2017.10.062</a>
Public note https://dx.doi.org/10.1016/j.athoracsur.2017.10.062
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 01/18/2018   29253463 29253463 01/18/2018 01/18/2018 Journal Article

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