Novel biomarker SYT12 may contribute to predicting papillary thyroid cancer outcomes. (Record no. 3000)

MARC details
000 -LEADER
fixed length control field 02283nam a22004337a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 180118s20182018 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2056-5623
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.4155/fsoa-2017-0087 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code PMC5729603 [pmc]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 29255621
245 ## - TITLE STATEMENT
Title Novel biomarker SYT12 may contribute to predicting papillary thyroid cancer outcomes.
251 ## - Source
Source Future Science OA. 4(1):FSO249, 2018 Jan
252 ## - Abbreviated Source
Abbreviated source Future Sci OA. 4(1):FSO249, 2018 Jan
253 ## - Journal Name
Journal name Future science OA
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Year 2018
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Manufacturer FY2018
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Date added to catalog 2018-01-18
520 ## - SUMMARY, ETC.
Abstract Aim: To investigate biomarkers for predicting papillary thyroid cancer outcomes.
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Abstract Conclusion: SYT12 has some prognostic significance in papillary thyroid cancer. Further validation studies in larger populations are warranted.
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Abstract Materials & methods: The expression of biomarkers (ITGA2, SYT12 and CDH3) was studied in a prospective cohort of patients with papillary thyroid cancer. Three outcomes of initial metastases, baseline status and longitudinal status were analyzed and correlated with the biomarkers.
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Abstract Results: SYT12 provided the best prediction of initial metastasis (sensitivity: 72%; specificity: 54%). SYT12 had the highest accuracy for predicting longitudinal status (sensitivity: 100%; specificity: 47%). The best performance for longitudinal status resulted from combining SYT12 with American Thyroid Association risk stratification, with sensitivity and specificity of 88 and 73%, respectively.
546 ## - LANGUAGE NOTE
Language note English
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Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
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Department Medicine/Endocrinology
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Department Pathology
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Department Surgery/Endocrine Surgery
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Department Surgery/General Surgery
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Medline publication type Journal Article
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Local Authors Burman, Kenneth D
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Local Authors Carroll, Nancy M
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Local Authors Felger, Erin A
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Local Authors Jonklaas, Jacqueline
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Local Authors Krishnan, Jayashree
790 ## - Authors
All authors Boyle L, Burman KD, Carrol N, Felger E, Jonklaas J, Klubo-Gwiezdzinska J, Krishnan J, Liu D, Loh YP, Murthy S
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.4155/fsoa-2017-0087">https://dx.doi.org/10.4155/fsoa-2017-0087</a>
Public note https://dx.doi.org/10.4155/fsoa-2017-0087
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 01/18/2018   29255621 29255621 01/18/2018 01/18/2018 Journal Article

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