MARC details
| 000 -LEADER |
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| fixed length control field |
03254nam a22003617a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
180619s20182018 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1052-3057 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1016/j.jstrokecerebrovasdis.2018.04.031 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
S1052-3057(18)30207-6 [pii] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
29776804 |
| 245 ## - TITLE STATEMENT |
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| Title |
Hemicraniectomy for Malignant Middle Cerebral Artery Syndrome: A Review of Functional Outcomes in Two High-Volume Stroke Centers. |
| 251 ## - Source |
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| Source |
Journal of Stroke & Cerebrovascular Diseases. 2018 May 15 |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
J STROKE CEREBROVASC DIS. 2018 May 15 |
| 253 ## - Journal Name |
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| Journal name |
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2018 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2018 |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2018-06-19 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND AND PURPOSE: Despite recent landmark randomized controlled trials showing significant benefits for hemicraniectomy (HCT) compared with medical therapy (MT) in patients with malignant middle cerebral artery infarction (MMCAI), HCT rates have not substantially increased in the United States. We sought to evaluate early outcomes in patients with MMCAI who were treated with HCT (cases) in comparison to patients treated with MT due to the perception of procedural futility by families (controls). |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: HCT is a critical and effective therapy for patients with MMCAI but cannot provide a guarantee of functional recovery. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Copyright Published by Elsevier Inc. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: We retrospectively evaluated consecutive patients with acute MMCAI treated in 2 tertiary care centers during a 7-year period. Pretreatment National Institutes of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS) at 3 months were documented. Functional independence (FI) and survival without severe disability (SWSD) were defined as mRS of 0-2 and 0-4, respectively. |
| 520 ## - SUMMARY, ETC. |
|---|
| Abstract |
RESULTS: A total of 66 patients (37 cases and 29 controls) fulfilled the study inclusion criteria (mean age 59+/-15 years, 52% men, median admission NIHSS score: 19 points [interquartile range {IQR}: 16-22]). Cases were younger (51+/-11 versus 68+/-13 years; P<.001) and tended to have lower median admission NIHSS than controls (18 [IQR:16-20] versus 20 [IQR:18-23]; P=.072). The rates of FI and SWSD at 3 months were higher in cases than controls (16% versus 0% [P=.031] and 62% versus 0% [P<.001]), while 3-month mortality was lower (24% versus 77%; P<.001). Multivariable Cox regression analyses adjusting for potential confounders identified HCT as the most important predictor of lower risk of 3-month mortality (hazard ratio: .02, 95% confidence interval: .01-0.10; P<.001). |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Neurology |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Chang, Jason J |
| 790 ## - Authors |
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| All authors |
Alexandrov AV, Alexandrov AW, Arthur AS, Boviatsis E, Chang JJ, Elijovich L, Goyal N, Hoit D, Ishfaq MF, Male S, Malkoff MD, Pandhi A, Tsivgoulis G, Voumvourakis K, Zand R |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.04.031">https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.04.031</a> |
| Public note |
https://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.04.031 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Journal Article |
| Item type description |
Article |
