MARC details
000 -LEADER |
fixed length control field |
03222nam a22004337a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
220926s20222022 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
1058-2916 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
00002480-900000000-98080 [pii] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1097/MAT.0000000000001658 [doi] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
35943389 |
245 ## - TITLE STATEMENT |
Title |
In-Hospital Left Ventricular Assist Devices Deactivation and Death Experience: a Single-Institution Retrospective Analysis. |
251 ## - Source |
Source |
ASAIO Journal. 2022 Jan 19 |
252 ## - Abbreviated Source |
Abbreviated source |
ASAIO J. 2022 Jan 19 |
253 ## - Journal Name |
Journal name |
ASAIO journal (American Society for Artificial Internal Organs : 1992) |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2022 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2022 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Publication date |
2022 Jan 19 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
aheadofprint |
266 ## - Date added to catalog |
Date added to catalog |
2022-09-26 |
501 ## - WITH NOTE |
Local holdings |
Available online from MWHC library: 2000 - present, Available in print through MWHC library: 1999 - 2003 |
520 ## - SUMMARY, ETC. |
Abstract |
Best practices for left ventricular assist devices (LVADs) deactivation at end-of-life (EOL) have yet to be elucidated. We conducted a single-institution retrospective review of patients who died following LVAD deactivation between January 2017 and March 2020. Data were obtained from institutional databases and electronic health record and were analyzed using descriptive statistics. Fifty-eight patients (70% male, 70% African American, median age 62 years) were categorized by implant strategy: bridge therapy (BT, N = 22, 38%) or destination therapy (DT, N = 36, 62%). Clinical events leading to deactivation were categorized either acute (e.g., stroke [N = 31, 53%]), gradual decline (N = 12, 21%), or complications during index hospitalization (N = 15, 26%). Implant strategy was not associated with clinical trajectory leading to EOL (p = 0.67), hospital unit of death (p = 0.13), or use of mechanical ventilation (p = 0.69) or renal replacement therapy (p = 0.81) during terminal hospitalization. Overall time from admission to code status change was mean 27.0 days (SD 30.3 days). Compared with BT patients, DT experienced earlier do-not-resuscitate (DNR) orders (p <= 0.01) and shorter survival post-deactivation (p <= 0.01). Deactivations after gradual decline tended to occur outside ICUs, compared with acute events or index implant-related complications (p = 0.04). Implant strategy was not associated with differences in EOL experience except regarding timing of DNR order and survival post-deactivation. Copyright (C) 2022 by the American Society for Artificial Internal Organs. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Heart & Vascular Institute |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Cardiovascular Disease Fellowship |
656 ## - INDEX TERM--OCCUPATION |
Department |
Medicine/Palliative Care |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Ahmed, Sara |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Groninger, Hunter |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Molina, Ezequiel |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Rao, Anirudh |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Sheikh, Farooq H |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Singh, Manavotam |
Institution Code |
MWHC |
Program |
Cardiovascular Disease Fellowship |
Degree |
MBBS |
Resident year |
Fellow PGY 4 |
790 ## - Authors |
All authors |
Ahmed S, Groninger H, Molina E, Rao A, Sheikh FH, Singh M |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1097/MAT.0000000000001658">https://dx.doi.org/10.1097/MAT.0000000000001658</a> |
Public note |
https://dx.doi.org/10.1097/MAT.0000000000001658 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |