In-Hospital Left Ventricular Assist Devices Deactivation and Death Experience: a Single-Institution Retrospective Analysis. (Record no. 356)

MARC details
000 -LEADER
fixed length control field 03222nam a22004337a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220926s20222022 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1058-2916
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 00002480-900000000-98080 [pii]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1097/MAT.0000000000001658 [doi]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 35943389
245 ## - TITLE STATEMENT
Title In-Hospital Left Ventricular Assist Devices Deactivation and Death Experience: a Single-Institution Retrospective Analysis.
251 ## - Source
Source ASAIO Journal. 2022 Jan 19
252 ## - Abbreviated Source
Abbreviated source ASAIO J. 2022 Jan 19
253 ## - Journal Name
Journal name ASAIO journal (American Society for Artificial Internal Organs : 1992)
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Year 2022
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Manufacturer FY2022
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Publication date 2022 Jan 19
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
266 ## - Date added to catalog
Date added to catalog 2022-09-26
501 ## - WITH NOTE
Local holdings Available online from MWHC library: 2000 - present, Available in print through MWHC library: 1999 - 2003
520 ## - SUMMARY, ETC.
Abstract Best practices for left ventricular assist devices (LVADs) deactivation at end-of-life (EOL) have yet to be elucidated. We conducted a single-institution retrospective review of patients who died following LVAD deactivation between January 2017 and March 2020. Data were obtained from institutional databases and electronic health record and were analyzed using descriptive statistics. Fifty-eight patients (70% male, 70% African American, median age 62 years) were categorized by implant strategy: bridge therapy (BT, N = 22, 38%) or destination therapy (DT, N = 36, 62%). Clinical events leading to deactivation were categorized either acute (e.g., stroke [N = 31, 53%]), gradual decline (N = 12, 21%), or complications during index hospitalization (N = 15, 26%). Implant strategy was not associated with clinical trajectory leading to EOL (p = 0.67), hospital unit of death (p = 0.13), or use of mechanical ventilation (p = 0.69) or renal replacement therapy (p = 0.81) during terminal hospitalization. Overall time from admission to code status change was mean 27.0 days (SD 30.3 days). Compared with BT patients, DT experienced earlier do-not-resuscitate (DNR) orders (p <= 0.01) and shorter survival post-deactivation (p <= 0.01). Deactivations after gradual decline tended to occur outside ICUs, compared with acute events or index implant-related complications (p = 0.04). Implant strategy was not associated with differences in EOL experience except regarding timing of DNR order and survival post-deactivation. Copyright (C) 2022 by the American Society for Artificial Internal Organs.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Heart & Vascular Institute
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Institution MedStar Washington Hospital Center
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Department Cardiovascular Disease Fellowship
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Department Medicine/Palliative Care
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Medline publication type Journal Article
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Local Authors Ahmed, Sara
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Local Authors Groninger, Hunter
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Local Authors Molina, Ezequiel
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Local Authors Rao, Anirudh
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Local Authors Sheikh, Farooq H
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Local Authors Singh, Manavotam
Institution Code MWHC
Program Cardiovascular Disease Fellowship
Degree MBBS
Resident year Fellow PGY 4
790 ## - Authors
All authors Ahmed S, Groninger H, Molina E, Rao A, Sheikh FH, Singh M
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1097/MAT.0000000000001658">https://dx.doi.org/10.1097/MAT.0000000000001658</a>
Public note https://dx.doi.org/10.1097/MAT.0000000000001658
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 09/26/2022   35943389 35943389 09/26/2022 09/26/2022 Journal Article

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