MARC details
000 -LEADER |
fixed length control field |
04502nam a22007337a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
190314s20192019 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
0002-9149 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1016/j.amjcard.2019.01.031 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
S0002-9149(19)30123-7 [pii] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
30738570 |
245 ## - TITLE STATEMENT |
Title |
Effects of Cangrelor as Adjunct Therapy to Percutaneous Coronary Intervention. |
251 ## - Source |
Source |
American Journal of Cardiology. 123(8):1228-1238, 2019 04 15. |
252 ## - Abbreviated Source |
Abbreviated source |
Am J Cardiol. 123(8):1228-1238, 2019 04 15. |
252 ## - Abbreviated Source |
Former abbreviated source |
Am J Cardiol. 2019 Jan 25 |
253 ## - Journal Name |
Journal name |
The American journal of cardiology |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2019 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2019 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
aheadofprint |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
ppublish |
266 ## - Date added to catalog |
Date added to catalog |
2019-03-14 |
268 ## - Previous citation |
-- |
American Journal of Cardiology. 2019 Jan 25 |
501 ## - WITH NOTE |
Local holdings |
Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006 |
520 ## - SUMMARY, ETC. |
Abstract |
Copyright (c) 2019. Published by Elsevier Inc. |
520 ## - SUMMARY, ETC. |
Abstract |
Percutaneous coronary intervention (PCI) in patients with angiographic evidence of intracoronary thrombus is associated with in-hospital and 30-day adverse clinical outcomes. Cangrelor, a direct, rapid-onset acting intravenous P2Y<sub>12</sub> receptor inhibitor, has been proved to be effective by reducing peri-PCI ischemic complications in subjects who underwent PCI. This study aimed to assess the angiographic and in-hospital clinical outcomes in all-comer patients receiving cangrelor immediately before PCI at a tertiary care center. The study analyzed consecutive unselected subjects treated with cangrelor at the time the decision was made to proceed with PCI. At the end of the procedure, all patients were transitioned to oral antiplatelet therapy. The target lesion angiographic assessment of Thrombolysis in myocardial infarction flow grade (TIMI-Flow), TIMI-thrombus grade (TIMI-Thrombus), myocardial blush grade, and TIMI-myocardial perfusion grade (TMPG) was performed before and post-PCI. Clinical events were recorded during the procedure and at discharge. In total, 223 patients (244 lesions) were included in the analysis (106, 97, and 20 patientswith TIMI-Flow 0/1, TIMI-Flow 2/3, and cardiogenic shock, respectively). The overall mean age was 63 +/- 12 years, 70% men and 38% with diabetes mellitus. Acute myocardial infarction was the main presentation (72%). The use of cangrelor improved TIMI-Flow, MGB, TMPG, and TIMI-Thrombus in patients with initial TIMI-Flow 0 to 2. Major bleeding rate was 2.0%. In conclusion, cangrelor was effective and safe in restoring TIMI-Flow 3, reducing thrombus burden and improving myocardial blush grade and TMPG when administered to unselected subjects who underwent PCI. Therefore, cangrelor should be considered in patients presenting with intracoronary thrombus before intervention. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Adenosine Monophosphate/aa [Analogs & Derivatives] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Coronary Thrombosis/th [Therapy] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Percutaneous Coronary Intervention/mt [Methods] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Adenosine Monophosphate/tu [Therapeutic Use] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Aged |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Coronary Angiography |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Coronary Thrombosis/di [Diagnosis] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Female |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Follow-Up Studies |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Humans |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Male |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Middle Aged |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Purinergic P2Y Receptor Antagonists/tu [Therapeutic Use] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Retrospective Studies |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Treatment Outcome |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Heart & Vascular Institute |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Beyene, Solomon |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Brathwaite, Echo |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Buchanan, Kyle |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Dan, Kazuhiro |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Dheendsa, Aaphtaab |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Gajanana, Deepakraj |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Garcia-Garcia, Hector M |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Hideo-Kajita, Alexandre |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Iantorno, Micaela |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Kolm, Paul |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Meirovich, Yael |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Melaku, Gebremedhin |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Ozaki, Yuichi |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Rogers, Toby |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Torguson, Rebecca |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Waksman, Ron |
790 ## - Authors |
All authors |
Beyene S, Brathwaite E, Buchanan K, Dan K, Dheendsa A, Gajanana D, Garcia-Garcia HM, Hideo-Kajita A, Iantorno M, Kolm P, Meirovich Y, Melaku G, Ozaki Y, Rogers T, Torguson R, Waksman R |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1016/j.amjcard.2019.01.031">https://dx.doi.org/10.1016/j.amjcard.2019.01.031</a> |
Public note |
https://dx.doi.org/10.1016/j.amjcard.2019.01.031 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |