MARC details
000 -LEADER |
fixed length control field |
03467nam a22005417a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
200709s20202020 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
0959-8049 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1016/j.ejca.2020.03.015 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
S0959-8049(20)30156-8 [pii] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
32375103 |
245 ## - TITLE STATEMENT |
Title |
Immune checkpoint inhibitor use and tuberculosis: a systematic review of the literature. |
251 ## - Source |
Source |
European Journal of Cancer. 132:168-175, 2020 06. |
252 ## - Abbreviated Source |
Abbreviated source |
Eur J Cancer. 132:168-175, 2020 06. |
252 ## - Abbreviated Source |
Former abbreviated source |
Eur J Cancer. 132:168-175, 2020 Jun. |
253 ## - Journal Name |
Journal name |
European journal of cancer (Oxford, England : 1990) |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2020 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2020 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
ppublish |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
ppublish |
266 ## - Date added to catalog |
Date added to catalog |
2020-07-09 |
268 ## - Previous citation |
-- |
European Journal of Cancer. 132:168-175, 2020 Jun. |
520 ## - SUMMARY, ETC. |
Abstract |
BACKGROUND: An amassing body of evidence exists to support an association between the use of immune checkpoint inhibitors (ICIs) and the development of tuberculosis (TB). |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSION: Findings from our systematic review indicate that PD-(L)1 inhibitors are linked to TB reactivation. TB activation can occur in various organs and TB-related fatalities have been reported. TB screening before starting immunotherapy should be considered in high-risk patient populations. Further research, including prospective studies with patients whose baseline TB status is known, is necessary to better understand the incidence of TB reactivation during ICI therapy and how best to manage TB that develops during immunotherapy. Copyright (c) 2020 Elsevier Ltd. All rights reserved. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: We performed a systematic review of the literature to assess the nature of this relationship using PubMed, EMBASE and meeting proceedings. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: We have identified 16 patients who developed active TB during immunotherapy. Median age was 61 (range: 49-87). Twelve (75%) were male and 4 (25%) were female. Lung cancer was the most common type of cancer (n = 8), followed by melanoma (n = 3) and head and neck cancer (n = 3). Median time to TB reactivation after initiation of ICI therapy was 6.3 months (range: 1-24 months). Two (13%) patients died of complications of TB (spinal cord compression, GI perforation). TB reactivation in organs (pericardium, bone, liver, and GI track; one each) other than the lungs has been documented. We did not find any cases of TB reactivation that occurred during anti-CTLA-4 therapy. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Antineoplastic Agents, Immunological/ae [Adverse Effects] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Neoplasms/dt [Drug Therapy] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Tuberculosis/ci [Chemically Induced] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Aged |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Aged, 80 and over |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Female |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Humans |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Male |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Middle Aged |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Neoplasms/pa [Pathology] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Prognosis |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Survival Rate |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Tuberculosis/pa [Pathology] |
656 ## - INDEX TERM--OCCUPATION |
Department |
MedStar Georgetown University Hospital Residents |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Zaemes, Jacob |
790 ## - Authors |
All authors |
Kim C, Zaemes J |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1016/j.ejca.2020.03.015">https://dx.doi.org/10.1016/j.ejca.2020.03.015</a> |
Public note |
https://dx.doi.org/10.1016/j.ejca.2020.03.015 |
-- |
https://dx.doi.org/10.1016/j.ejca.2020.03.015 |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1016/j.ejca.2020.03.015">https://dx.doi.org/10.1016/j.ejca.2020.03.015</a> |
Public note |
https://dx.doi.org/10.1016/j.ejca.2020.03.015 |
-- |
https://dx.doi.org/10.1016/j.ejca.2020.03.015 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |