MARC details
| 000 -LEADER |
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| fixed length control field |
03712nam a22003737a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
200709s20202020 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0195-668X |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1093/eurheartj/ehaa051 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
5762637 [pii] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
PMC7205467 [pmc] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
32112560 |
| 245 ## - TITLE STATEMENT |
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| Title |
Cardiovascular magnetic resonance in immune checkpoint inhibitor-associated myocarditis. |
| 251 ## - Source |
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| Source |
European Heart Journal. 41(18):1733-1743, 2020 May 07. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Eur Heart J. 41(18):1733-1743, 2020 May 07. |
| 253 ## - Journal Name |
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| Journal name |
European heart journal |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2020 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2020 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
ppublish |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2020-07-09 |
| 501 ## - WITH NOTE |
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| Local holdings |
Available online from MWHC library: 1996 - present (after 1 year), Available in print through MWHC library: 1999 - 2006 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
AIMS: Myocarditis is a potentially fatal complication of immune checkpoint inhibitors (ICI). Sparse data exist on the use of cardiovascular magnetic resonance (CMR) in ICI-associated myocarditis. In this study, the CMR characteristics and the association between CMR features and cardiovascular events among patients with ICI-associated myocarditis are presented. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSION: These data suggest caution in reliance on LGE or a qualitative T2-STIR-only approach for the exclusion of ICI-associated myocarditis. Copyright Published on behalf of the European Society of Cardiology. All rights reserved. (c) The Author(s) 2020. For permissions, please email: [email protected]. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS AND RESULTS: From an international registry of patients with ICI-associated myocarditis, clinical, CMR, and histopathological findings were collected. Major adverse cardiovascular events (MACE) were a composite of cardiovascular death, cardiogenic shock, cardiac arrest, and complete heart block. In 103 patients diagnosed with ICI-associated myocarditis who had a CMR, the mean left ventricular ejection fraction (LVEF) was 50%, and 61% of patients had an LVEF >=50%. Late gadolinium enhancement (LGE) was present in 48% overall, 55% of the reduced EF, and 43% of the preserved EF cohort. Elevated T2-weighted short tau inversion recovery (STIR) was present in 28% overall, 30% of the reduced EF, and 26% of the preserved EF cohort. The presence of LGE increased from 21.6%, when CMR was performed within 4 days of admission to 72.0% when CMR was performed on Day 4 of admission or later. Fifty-six patients had cardiac pathology. Late gadolinium enhancement was present in 35% of patients with pathological fibrosis and elevated T2-weighted STIR signal was present in 26% with a lymphocytic infiltration. Forty-one patients (40%) had MACE over a follow-up time of 5 months. The presence of LGE, LGE pattern, or elevated T2-weighted STIR were not associated with MACE. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Heart & Vascular Institute |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Barac, Ana |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Forrestal, Brian J |
| 790 ## - Authors |
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| All authors |
Alvi RM, Armanious M, Awadalla M, Baksi AJ, Barac A, Chen CL, Coelho-Filho OR, Cohen JV, Damrongwatanasuk R, Ederhy S, Forrestal BJ, Fradley MG, Ganatra S, Golden DLA, Groarke JD, Gupta D, Hassan MZO, Heinzerling LM, Jones-O'Connor M, Kirchberger MC, Kwong RY, Lawrence DP, Lyon AR, Mahmood SS, Mahmoudi M, Mercurio V, Moslehi JJ, Mulligan C, Murphy SP, Neilan TG, Nohria A, Reynolds KL, Rizvi MA, Rokicki A, Sahni G, Stone JR, Sullivan RJ, Thavendiranathan P, Thuny F, Tocchetti CG, Weinsaft JW, Yang EH, Zhang L, Zlotoff DA |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1093/eurheartj/ehaa051">https://dx.doi.org/10.1093/eurheartj/ehaa051</a> |
| Public note |
https://dx.doi.org/10.1093/eurheartj/ehaa051 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
