MARC details
000 -LEADER |
fixed length control field |
02871nam a22003617a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
220511s20222022 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
0003-4975 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1016/j.athoracsur.2022.03.071 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
S0003-4975(22)00522-7 [pii] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
35452663 |
245 ## - TITLE STATEMENT |
Title |
Outcomes in Smaller Body Size Adults after HeartMate 3 Left Ventricular Assist Device Implantation. |
251 ## - Source |
Source |
Annals of Thoracic Surgery. 2022 Apr 19 |
252 ## - Abbreviated Source |
Abbreviated source |
Ann Thorac Surg. 2022 Apr 19 |
253 ## - Journal Name |
Journal name |
The Annals of thoracic surgery |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2022 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2022 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Publication date |
2022 Apr 19 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
aheadofprint |
266 ## - Date added to catalog |
Date added to catalog |
2022-05-11 |
520 ## - SUMMARY, ETC. |
Abstract |
BACKGROUND: Outcomes in patients with smaller body size following HeartMate 3 Left Ventricular Assist Device (HM3) implantation are not well characterized. We sought to evaluate outcomes in smaller vs. larger BSA patients in the MOMENTUM 3 pivotal trial and its Continued Access Protocol cohort. |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSIONS: Outcomes following HM3 implantation were comparable between small and large patients. Smaller body size should not be used to deny HM3 implantation in patients who are otherwise suitable durable MCS candidates. Copyright © 2022 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved. |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: The analysis cohort included 1015 HM3 patients divided into 2 groups: BSA<=1.70 m2 (small patients, n=82) and BSA>1.70 m2 (large patients, n=933). The composite primary endpoint was survival at 2-years free of disabling stroke or reoperation to replace or remove a malfunctioning device. Adverse events were compared between groups. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: Smaller patients were more frequently women (56.1% vs. 17.7%, P<.001), had lower prevalence of diabetes (28.1% vs. 43.9%, P=.005) and hypertension (51.2% vs. 71.9%, P<.001), larger median indexed LVEDD (normalized by BSA, 40 vs. 33 mm/m2, P<.001), and lower median serum creatinine (1.1 vs. 1.3 mg/dl, P<.001). The proportion of patients achieving the composite endpoint at 2-years was 77% in both groups (adjusted HR = 1.14 [95% confidence interval: 0.68-1.91], P=.62). Two-year adverse event rates were also similar between groups except for sepsis (6.1% vs. 14.9%, P=.029) and cardiac arrhythmias (24.4% vs. 35.3%, P=.005), which were higher in the larger patients. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Heart & Vascular Institute |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Molina, Ezequiel |
790 ## - Authors |
All authors |
Bourque K, Chuang J, Cleveland JC Jr, Cowger J, Goldstein DJ, Horstmanshof D, Lee S, Mehra MR, Molina EJ, Naka Y, Salerno CT, Uriel N |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1016/j.athoracsur.2022.03.071">https://dx.doi.org/10.1016/j.athoracsur.2022.03.071</a> |
Public note |
https://dx.doi.org/10.1016/j.athoracsur.2022.03.071 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |