Outcomes in Smaller Body Size Adults after HeartMate 3 Left Ventricular Assist Device Implantation. (Record no. 553)

MARC details
000 -LEADER
fixed length control field 02871nam a22003617a 4500
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fixed length control field 220511s20222022 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0003-4975
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1016/j.athoracsur.2022.03.071 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code S0003-4975(22)00522-7 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 35452663
245 ## - TITLE STATEMENT
Title Outcomes in Smaller Body Size Adults after HeartMate 3 Left Ventricular Assist Device Implantation.
251 ## - Source
Source Annals of Thoracic Surgery. 2022 Apr 19
252 ## - Abbreviated Source
Abbreviated source Ann Thorac Surg. 2022 Apr 19
253 ## - Journal Name
Journal name The Annals of thoracic surgery
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2022
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2022
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2022 Apr 19
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
266 ## - Date added to catalog
Date added to catalog 2022-05-11
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Outcomes in patients with smaller body size following HeartMate 3 Left Ventricular Assist Device (HM3) implantation are not well characterized. We sought to evaluate outcomes in smaller vs. larger BSA patients in the MOMENTUM 3 pivotal trial and its Continued Access Protocol cohort.
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: Outcomes following HM3 implantation were comparable between small and large patients. Smaller body size should not be used to deny HM3 implantation in patients who are otherwise suitable durable MCS candidates. Copyright © 2022 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
520 ## - SUMMARY, ETC.
Abstract METHODS: The analysis cohort included 1015 HM3 patients divided into 2 groups: BSA<=1.70 m2 (small patients, n=82) and BSA>1.70 m2 (large patients, n=933). The composite primary endpoint was survival at 2-years free of disabling stroke or reoperation to replace or remove a malfunctioning device. Adverse events were compared between groups.
520 ## - SUMMARY, ETC.
Abstract RESULTS: Smaller patients were more frequently women (56.1% vs. 17.7%, P<.001), had lower prevalence of diabetes (28.1% vs. 43.9%, P=.005) and hypertension (51.2% vs. 71.9%, P<.001), larger median indexed LVEDD (normalized by BSA, 40 vs. 33 mm/m2, P<.001), and lower median serum creatinine (1.1 vs. 1.3 mg/dl, P<.001). The proportion of patients achieving the composite endpoint at 2-years was 77% in both groups (adjusted HR = 1.14 [95% confidence interval: 0.68-1.91], P=.62). Two-year adverse event rates were also similar between groups except for sepsis (6.1% vs. 14.9%, P=.029) and cardiac arrhythmias (24.4% vs. 35.3%, P=.005), which were higher in the larger patients.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element IN PROCESS -- NOT YET INDEXED
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Heart & Vascular Institute
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Molina, Ezequiel
790 ## - Authors
All authors Bourque K, Chuang J, Cleveland JC Jr, Cowger J, Goldstein DJ, Horstmanshof D, Lee S, Mehra MR, Molina EJ, Naka Y, Salerno CT, Uriel N
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1016/j.athoracsur.2022.03.071">https://dx.doi.org/10.1016/j.athoracsur.2022.03.071</a>
Public note https://dx.doi.org/10.1016/j.athoracsur.2022.03.071
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
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Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 05/11/2022   35452663 35452663 05/11/2022 05/11/2022 Journal Article

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