MARC details
000 -LEADER |
fixed length control field |
04488nam a22008177a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
201229s20202020 xxu||||| |||| 00| 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
International Standard Serial Number |
2152-2669 |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1016/j.clml.2020.09.011 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
S2152-2650(20)30549-8 [pii] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
33132102 |
245 ## - TITLE STATEMENT |
Title |
Clearance of Hepatitis C Virus (HCV) Is Associated With Improved Outcomes in HCV-Associated Lymphoma. |
251 ## - Source |
Source |
Clinical lymphoma, myeloma & leukemia. 21(2):e185-e193, 2021 02. |
252 ## - Abbreviated Source |
Abbreviated source |
Clin Lymphoma Myeloma Leuk. 21(2):e185-e193, 2021 02. |
252 ## - Abbreviated Source |
Former abbreviated source |
Clin Lymphoma Myeloma Leuk. 2020 Oct 02 |
253 ## - Journal Name |
Journal name |
Clinical lymphoma, myeloma & leukemia |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2021 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2021 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
aheadofprint |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
ppublish |
266 ## - Date added to catalog |
Date added to catalog |
2020-12-29 |
268 ## - Previous citation |
-- |
Clinical lymphoma, myeloma & leukemia. 2020 Oct 02 |
269 ## - Original dates |
Original fiscal year |
FY2021 |
520 ## - SUMMARY, ETC. |
Abstract |
BACKGROUND: Improved hepatitis C virus (HCV) clearance due to directly acting antiviral agents has led to remarkably improved outcomes of indolent HCV-associated non-Hodgkin lymphoma (NHL). The impact of directly acting antivirals on the outcomes of aggressive NHL is still under investigation. Characteristics of HCV-associated NHL in black patients are not well characterized. We report outcomes of HCV-associated NHL compared to their HCV-negative counterparts in a predominantly black population. |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSION: HCV clearance is positively associated with lymphoma outcomes in black patients. Patients who clear HCV have noninferior outcomes to HCV- patients, while those who fail to clear HCV have significantly worse outcomes. Copyright (c) 2020 Elsevier Inc. All rights reserved. |
520 ## - SUMMARY, ETC. |
Abstract |
PATIENTS AND METHODS: Patients with lymphoma between January 2007 and December 2017 were retrospectively studied. Depending on presence or absence of HCV RNA, patients were grouped into HCV positive (HCV+) and HCV negative (HCV-) cohorts. Depending on virologic clearance (VC), HCV+ were classified into HCV+ with VC and HCV+ without VC. Overall response rate (ORR), complete response, overall survival (OS), and progression-free survival (PFS) of HCV+ patients with and without VC were compared to HCV- patients. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: Of 397 patients with lymphoma, 40 had HCV. Black comprised 90% of HCV+ patients. Diffuse large B-cell lymphoma was most frequent (47%) in the HCV+ group. HCV+ patients without VC had significantly worse OS and PFS compared to HCV- patients. There were no differences in ORR, complete response, PFS, and OS of HCV+ patients with VC and HCV- patients. These results were consistent in subgroups of diffuse large B-cell lymphoma and aggressive lymphoma. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Antiviral Agents/tu [Therapeutic Use] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Hepacivirus/ip [Isolation & Purification] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Hepatitis C/dt [Drug Therapy] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Lymphoma, Non-Hodgkin/mo [Mortality] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Adolescent |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Adult |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Aged |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Aged, 80 and over |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Female |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Hepacivirus/ge [Genetics] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Hepatitis C/vi [Virology] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Humans |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Lymphoma, Non-Hodgkin/th [Therapy] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Lymphoma, Non-Hodgkin/vi [Virology] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Male |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Middle Aged |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Progression-Free Survival |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Retrospective Studies |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
RNA, Viral/ip [Isolation & Purification] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Young Adult |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Health Research Institute |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Heart & Vascular Institute |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
Washington Cancer Institute |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
Washington Cancer Institute H |
656 ## - INDEX TERM--OCCUPATION |
Department |
Medicine/Infectious Diseases |
656 ## - INDEX TERM--OCCUPATION |
Department |
Medicine/Internal Medicine |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Adhikari, Tripti |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Al-Shbool, Ghassan |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Baez-Sosa, Valentina |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Desai, Sanjal |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Fernandez, Stephen J |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Fishbein, Dawn |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Hameed, Rumaisa |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Malkovska, Vera |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Paku, Emily |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Stingo, Facundo |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Vakiti, Anusha |
790 ## - Authors |
All authors |
Adhikari T, Al-Shbool G, Baez-Sosa V, Desai SH, Fernandez S, Fishbein D, Hameed R, Malkovska V, Paku E, Stingo F, Vakiti A |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1016/j.clml.2020.09.011">https://dx.doi.org/10.1016/j.clml.2020.09.011</a> |
Public note |
https://dx.doi.org/10.1016/j.clml.2020.09.011 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |