Clearance of Hepatitis C Virus (HCV) Is Associated With Improved Outcomes in HCV-Associated Lymphoma. (Record no. 5848)

MARC details
000 -LEADER
fixed length control field 04488nam a22008177a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 201229s20202020 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2152-2669
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1016/j.clml.2020.09.011 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code S2152-2650(20)30549-8 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 33132102
245 ## - TITLE STATEMENT
Title Clearance of Hepatitis C Virus (HCV) Is Associated With Improved Outcomes in HCV-Associated Lymphoma.
251 ## - Source
Source Clinical lymphoma, myeloma & leukemia. 21(2):e185-e193, 2021 02.
252 ## - Abbreviated Source
Abbreviated source Clin Lymphoma Myeloma Leuk. 21(2):e185-e193, 2021 02.
252 ## - Abbreviated Source
Former abbreviated source Clin Lymphoma Myeloma Leuk. 2020 Oct 02
253 ## - Journal Name
Journal name Clinical lymphoma, myeloma & leukemia
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2021
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2021
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
266 ## - Date added to catalog
Date added to catalog 2020-12-29
268 ## - Previous citation
-- Clinical lymphoma, myeloma & leukemia. 2020 Oct 02
269 ## - Original dates
Original fiscal year FY2021
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Improved hepatitis C virus (HCV) clearance due to directly acting antiviral agents has led to remarkably improved outcomes of indolent HCV-associated non-Hodgkin lymphoma (NHL). The impact of directly acting antivirals on the outcomes of aggressive NHL is still under investigation. Characteristics of HCV-associated NHL in black patients are not well characterized. We report outcomes of HCV-associated NHL compared to their HCV-negative counterparts in a predominantly black population.
520 ## - SUMMARY, ETC.
Abstract CONCLUSION: HCV clearance is positively associated with lymphoma outcomes in black patients. Patients who clear HCV have noninferior outcomes to HCV- patients, while those who fail to clear HCV have significantly worse outcomes. Copyright (c) 2020 Elsevier Inc. All rights reserved.
520 ## - SUMMARY, ETC.
Abstract PATIENTS AND METHODS: Patients with lymphoma between January 2007 and December 2017 were retrospectively studied. Depending on presence or absence of HCV RNA, patients were grouped into HCV positive (HCV+) and HCV negative (HCV-) cohorts. Depending on virologic clearance (VC), HCV+ were classified into HCV+ with VC and HCV+ without VC. Overall response rate (ORR), complete response, overall survival (OS), and progression-free survival (PFS) of HCV+ patients with and without VC were compared to HCV- patients.
520 ## - SUMMARY, ETC.
Abstract RESULTS: Of 397 patients with lymphoma, 40 had HCV. Black comprised 90% of HCV+ patients. Diffuse large B-cell lymphoma was most frequent (47%) in the HCV+ group. HCV+ patients without VC had significantly worse OS and PFS compared to HCV- patients. There were no differences in ORR, complete response, PFS, and OS of HCV+ patients with VC and HCV- patients. These results were consistent in subgroups of diffuse large B-cell lymphoma and aggressive lymphoma.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Antiviral Agents/tu [Therapeutic Use]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Hepacivirus/ip [Isolation & Purification]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Hepatitis C/dt [Drug Therapy]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Lymphoma, Non-Hodgkin/mo [Mortality]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Adolescent
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Adult
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aged
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aged, 80 and over
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Hepacivirus/ge [Genetics]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Hepatitis C/vi [Virology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Lymphoma, Non-Hodgkin/th [Therapy]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Lymphoma, Non-Hodgkin/vi [Virology]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Middle Aged
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Progression-Free Survival
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Retrospective Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element RNA, Viral/ip [Isolation & Purification]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Young Adult
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Health Research Institute
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Heart & Vascular Institute
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution Washington Cancer Institute
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution Washington Cancer Institute H
656 ## - INDEX TERM--OCCUPATION
Department Medicine/Infectious Diseases
656 ## - INDEX TERM--OCCUPATION
Department Medicine/Internal Medicine
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Adhikari, Tripti
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Al-Shbool, Ghassan
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Baez-Sosa, Valentina
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Desai, Sanjal
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Fernandez, Stephen J
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Fishbein, Dawn
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Hameed, Rumaisa
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Malkovska, Vera
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Paku, Emily
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Stingo, Facundo
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Vakiti, Anusha
790 ## - Authors
All authors Adhikari T, Al-Shbool G, Baez-Sosa V, Desai SH, Fernandez S, Fishbein D, Hameed R, Malkovska V, Paku E, Stingo F, Vakiti A
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1016/j.clml.2020.09.011">https://dx.doi.org/10.1016/j.clml.2020.09.011</a>
Public note https://dx.doi.org/10.1016/j.clml.2020.09.011
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 12/29/2020   33132102 33132102 12/29/2020 12/29/2020 Journal Article

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