MARC details
| 000 -LEADER |
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| fixed length control field |
03485nam a22004337a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
210628s20212021 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
1748-6815 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1016/j.bjps.2020.10.054 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
S1748-6815(20)30551-9 [pii] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
33248934 |
| 245 ## - TITLE STATEMENT |
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| Title |
The "Double hit": Free tissue transfer is optimal in comorbid population with irradiated wounds for successful limb salvage. |
| 251 ## - Source |
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| Source |
Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS. 74(6):1246-1252, 2021 Jun. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
J Plast Reconstr Aesthet Surg. 74(6):1246-1252, 2021 Jun. |
| 253 ## - Journal Name |
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| Journal name |
Journal of plastic, reconstructive & aesthetic surgery : JPRAS |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Publication date |
2021 Jun |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
ppublish |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2021-06-28 |
| 501 ## - WITH NOTE |
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| Local holdings |
Available online from MWHC library: 1995 - present |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: Radiation therapy causes histopathologic changes in tissues, including fibrosis, loss of tissue planes, and vascular damage, which can lead to chronic wound formation. Patients with nonhealing, irradiated wounds and comorbidities that affect microvasculature suffer a "double hit", which leads to delayed wound healing. Local wound care and grafts are commonly insufficient. In this study, we evaluated limb salvage outcomes and long-term complications after free tissue transfer (FTT) in patients with chronic, irradiated leg wounds. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: Radiation therapy in a comorbid population often leads to the formation of chronic nonhealing wounds. We advocate for earlier consideration of FTT to provide healthy vascularized tissues, thereby avoiding prolonged wound care and patient burden. Successful limb salvage outcomes can be achieved. Copyright (c) 2020 Elsevier Ltd. All rights reserved. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: We retrospectively reviewed patients with irradiated lower extremity wounds who underwent FTT from 2012 to 2017. Primary outcomes included limb salvage, ambulation, and overall flap success. Reconstruction involved complete excision of irradiated tissue and coverage with well-vascularized tissue. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: Seven free flaps in six patients were identified. Average age was 68.4 years and average BMI was 27.8kg/m2. Comorbid conditions included hypertension (57.1%), peripheral vascular disease (57.1%), underlying hypercoagulability (42.9%), diabetes (14.3%), and tobacco use (14.3%). Wounds were present for an average of 25.5 months prior to FTT. Donor sites included anterolateral thigh (71.4%), vastus lateralis (14.3%), and latissimus dorsi (14.3%). Overall flap success rate was 100% with one patient requiring reoperation for dehiscence. Limb salvage rate was 85.7% with one patient undergoing elective amputation due to pain. All patients could ambulate (one used a prosthesis) at a mean follow-up time of 1.4 years. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Health Research Institute |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
MedStar General Surgery Residency |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Surgery/Plastic Surgery |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Black, Cara K |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Deldar, Romina |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Fan, Kenneth L |
| 790 ## - Authors |
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| All authors |
Black CK, Deldar R, Evans KK, Fan KL, Luvisa K, Wirth P, Zolper EG |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1016/j.bjps.2020.10.054">https://dx.doi.org/10.1016/j.bjps.2020.10.054</a> |
| Public note |
https://dx.doi.org/10.1016/j.bjps.2020.10.054 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
