MARC details
| 000 -LEADER |
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| fixed length control field |
03903nam a22005657a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
211101s20212021 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
2150-1319 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
34467805 |
| 245 ## - TITLE STATEMENT |
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| Title |
Oral Prescription Opioids as a High-Risk Indicator for Hepatitis C Infection: Another Step Toward HCV Elimination. |
| 251 ## - Source |
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| Source |
Journal of Primary Care & Community Health. 12:21501327211034379, 2021 Jan-Dec. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
J. prim. care community health. 12:21501327211034379, 2021 Jan-Dec. |
| 252 ## - Abbreviated Source |
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| Former abbreviated source |
J. prim. care community health. 12:21501327211034379, 2021 Jan-Dec. |
| 253 ## - Journal Name |
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| Journal name |
Journal of primary care & community health |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2022 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
ppublish |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2021-11-01 |
| 268 ## - Previous citation |
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| -- |
Journal of Primary Care & Community Health. 12:21501327211034379, 2021 Jan-Dec. |
| 269 ## - Original dates |
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| Original fiscal year |
FY2022 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: The opioid epidemic across the U.S. poses an array of public health concerns, especially HCV transmission. HCV is now widely curable, yet incident rates are increasing due to the opioid epidemic. Despite the established trajectory from oral prescription opioids (OPOs) to opioid use disorder (OUD), OUD to injection drug use (IDU), and IDU to hepatitis C virus (HCV), OPOs are not a defined risk factor (RF) for HCV infection. The objective of this study was to observe rates of HCV testing and Ab reactivity (HCVAb+) in patients receiving OPOs to substantiate them as a RF, ultimately contributing to HCV elimination. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: (1) In a large population prescribed oral opioids, HCVAb+ was 8.6%, higher than our previously published data (2.5%) and the US rate (1.7%); (2) only 20% of patients diagnosed with OUD were tested; and (3) only 25% of HCVAb+ patients were classified with OUD; this suggests underreporting of OUD in this population. Primary Care and Community Health Recommendations: (1) Re-testing for HCV in patients taking OPOs; (2) increased HCV testing among OUD patients; and (3) improved surveillance and reporting of OUD. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: Data from MedStar Health patients receiving OPOs from 1/2017 to 12/2018 were collected and analyzed using chi-squared or student t-tests and logistic regression for uni- or multi-variable analyses, respectively. Statistical significance was defined as P < .05; Epi Info and SAS v 9.4 were used for statistical analyses; IRB approval was received. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: There were 115 415 individuals prescribed OPOs over the study period. In this population, 8.6% (932) were HCVAb+ when tested and not previously diagnosed (10 900); 3.4% (3893) had an OUD diagnosis, 20.6% (803) of whom were HCV tested; 25.4% (361) of all HCVAb+ (1421) had an OUD diagnosis. OUD (ORadj 8.53 [7.22-10.07]) was an independent predictor of HCVAb+ in this population. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Hepatitis C |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Opioid-Related Disorders |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Analgesics, Opioid/tu [Therapeutic Use] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Hepacivirus |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Hepatitis C/di [Diagnosis] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Hepatitis C/dt [Drug Therapy] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Hepatitis C/ep [Epidemiology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Opioid-Related Disorders/ep [Epidemiology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Prescriptions |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Health Research Institute |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Heart & Vascular Institute |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Medicine/Infectious Diseases |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Fernandez, Stephen J |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Fishbein, Dawn |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Paku, Emily |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Tefera, Eshetu |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Timalsina, Utsav |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Wilkerson, Brittany |
| 790 ## - Authors |
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| All authors |
Fernandez S, Fishbein D, Hack B, Paku E, Tefera E, Timalsina U, Wilkerson B |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1177/21501327211034379">https://dx.doi.org/10.1177/21501327211034379</a> |
| Public note |
https://dx.doi.org/10.1177/21501327211034379 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
