Treatment of refractory overactive bladder with OnabotulinumtoxinA vs PTNS: TROOP trial. (Record no. 839)

MARC details
000 -LEADER
fixed length control field 03715nam a22005537a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220221s20222022 xxu||||| |||| 00| 0 eng d
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/s00192-021-05030-3 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/s00192-021-05030-3 [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 34993598
245 ## - TITLE STATEMENT
Title Treatment of refractory overactive bladder with OnabotulinumtoxinA vs PTNS: TROOP trial.
251 ## - Source
Source International Urogynecology Journal. 33(4):851-860, 2022 Apr.
252 ## - Abbreviated Source
Abbreviated source Int Urogynecol J Pelvic Floor Dysfunct. 33(4):851-860, 2022 Apr.
252 ## - Abbreviated Source
Former abbreviated source Int Urogynecol J Pelvic Floor Dysfunct. 2022 Jan 07
253 ## - Journal Name
Journal name International urogynecology journal
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2022
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2022
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2022 Jan 07
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
266 ## - Date added to catalog
Date added to catalog 2022-02-21
268 ## - Previous citation
-- International Urogynecology Journal. 2022 Jan 07
501 ## - WITH NOTE
Local holdings Available online through MWHC library: 2010 - present
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: BTX resulted in significantly greater improvement in urgency and UUI than PTNS, but no difference in success based on PGII and OABq-SSS, which may be due to a lack of power. Copyright (c) 2021. The International Urogynecological Association.
520 ## - SUMMARY, ETC.
Abstract INTRODUCTION AND HYPOTHESIS: We hypothesized that patients with refractory overactive bladder (rOAB) have similar improvement with percutaneous tibial nerve stimulation (PTNS) and OnabotulinumtoxinA (BTX).
520 ## - SUMMARY, ETC.
Abstract METHODS: This multicenter cohort study compared BTX and PTNS in women with rOAB. Baseline information included Overactive Bladder Questionnaire (OABq) short form, Urinary Distress Inventory-6 (UDI-6), and voiding diary. Primary outcome was cure, defined as "very much better" or "much better" on the Patient Global Impression of Improvement (PGII) AND a reduction in OABq symptom severity scale (SSS) >=10 at 3 months after treatment. Assuming 80% power to detect a ten-point difference in OABq-SSS, 80 participants were required per group.
520 ## - SUMMARY, ETC.
Abstract RESULTS: A total of 150 patients were enrolled; 97 completed 3 months of therapy and were included. At baseline, BTX patients had more detrusor overactivity (70% vs 40%, p = 0.025), urgency incontinence (UUI; OABq-SSS#6 4 vs 3, p = 0.02, SSS 65 vs 56, p = 0.04), but similar health-related quality of life (HRQL 49 vs 54, p = 0.28), voids (7 vs 8, p = 0.13), and UUI episodes (2 vs 2, p = 1.0). At 3 months, cure rates were similar: BTX 50% vs PTNS 44.2% (p = 0.56). Both groups had improved SSS (-37 vs -29, p = 0.08) and HRQL (31 vs 24, p = 0.14). Patients receiving BTX had a greater improvement in urgency (DELTAOABq-SSS#2-3 vs -2; p = 0.02) and UUI (DELTAOABq-SSS#6-2 vs -1; p = 0.02). No characteristics were predictive of cure.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Botulinum Toxins, Type A
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Transcutaneous Electric Nerve Stimulation
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Urinary Bladder, Overactive
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Botulinum Toxins, Type A/tu [Therapeutic Use]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cohort Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Quality of Life
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Tibial Nerve
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Treatment Outcome
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Urinary Bladder, Overactive/dt [Drug Therapy]
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Health Research Institute
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Obstetrics and Gynecology/Female Pelvic Medicine and Reconstructive Surgery
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Gutman, Robert E
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Tefera, Eshetu
790 ## - Authors
All authors Cameron AP, Gutman RE, Jeppson PC, Khavari R, Kopcsay KS, Marczak TD, Tefera E
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1007/s00192-021-05030-3">https://dx.doi.org/10.1007/s00192-021-05030-3</a>
Public note https://dx.doi.org/10.1007/s00192-021-05030-3
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 02/21/2022   34993598 34993598 02/21/2022 02/21/2022 Journal Article

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