MARC details
000 -LEADER |
fixed length control field |
03715nam a22005537a 4500 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
220221s20222022 xxu||||| |||| 00| 0 eng d |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1007/s00192-021-05030-3 [doi] |
024 ## - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.1007/s00192-021-05030-3 [pii] |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
Ovid MEDLINE(R) |
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
PMID |
34993598 |
245 ## - TITLE STATEMENT |
Title |
Treatment of refractory overactive bladder with OnabotulinumtoxinA vs PTNS: TROOP trial. |
251 ## - Source |
Source |
International Urogynecology Journal. 33(4):851-860, 2022 Apr. |
252 ## - Abbreviated Source |
Abbreviated source |
Int Urogynecol J Pelvic Floor Dysfunct. 33(4):851-860, 2022 Apr. |
252 ## - Abbreviated Source |
Former abbreviated source |
Int Urogynecol J Pelvic Floor Dysfunct. 2022 Jan 07 |
253 ## - Journal Name |
Journal name |
International urogynecology journal |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Year |
2022 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Manufacturer |
FY2022 |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Publication date |
2022 Jan 07 |
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
Publication status |
ppublish |
266 ## - Date added to catalog |
Date added to catalog |
2022-02-21 |
268 ## - Previous citation |
-- |
International Urogynecology Journal. 2022 Jan 07 |
501 ## - WITH NOTE |
Local holdings |
Available online through MWHC library: 2010 - present |
520 ## - SUMMARY, ETC. |
Abstract |
CONCLUSIONS: BTX resulted in significantly greater improvement in urgency and UUI than PTNS, but no difference in success based on PGII and OABq-SSS, which may be due to a lack of power. Copyright (c) 2021. The International Urogynecological Association. |
520 ## - SUMMARY, ETC. |
Abstract |
INTRODUCTION AND HYPOTHESIS: We hypothesized that patients with refractory overactive bladder (rOAB) have similar improvement with percutaneous tibial nerve stimulation (PTNS) and OnabotulinumtoxinA (BTX). |
520 ## - SUMMARY, ETC. |
Abstract |
METHODS: This multicenter cohort study compared BTX and PTNS in women with rOAB. Baseline information included Overactive Bladder Questionnaire (OABq) short form, Urinary Distress Inventory-6 (UDI-6), and voiding diary. Primary outcome was cure, defined as "very much better" or "much better" on the Patient Global Impression of Improvement (PGII) AND a reduction in OABq symptom severity scale (SSS) >=10 at 3 months after treatment. Assuming 80% power to detect a ten-point difference in OABq-SSS, 80 participants were required per group. |
520 ## - SUMMARY, ETC. |
Abstract |
RESULTS: A total of 150 patients were enrolled; 97 completed 3 months of therapy and were included. At baseline, BTX patients had more detrusor overactivity (70% vs 40%, p = 0.025), urgency incontinence (UUI; OABq-SSS#6 4 vs 3, p = 0.02, SSS 65 vs 56, p = 0.04), but similar health-related quality of life (HRQL 49 vs 54, p = 0.28), voids (7 vs 8, p = 0.13), and UUI episodes (2 vs 2, p = 1.0). At 3 months, cure rates were similar: BTX 50% vs PTNS 44.2% (p = 0.56). Both groups had improved SSS (-37 vs -29, p = 0.08) and HRQL (31 vs 24, p = 0.14). Patients receiving BTX had a greater improvement in urgency (DELTAOABq-SSS#2-3 vs -2; p = 0.02) and UUI (DELTAOABq-SSS#6-2 vs -1; p = 0.02). No characteristics were predictive of cure. |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Botulinum Toxins, Type A |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Transcutaneous Electric Nerve Stimulation |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
*Urinary Bladder, Overactive |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Botulinum Toxins, Type A/tu [Therapeutic Use] |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Cohort Studies |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Female |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Humans |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Male |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Quality of Life |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Tibial Nerve |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Treatment Outcome |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Urinary Bladder, Overactive/dt [Drug Therapy] |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Health Research Institute |
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
Institution |
MedStar Washington Hospital Center |
656 ## - INDEX TERM--OCCUPATION |
Department |
Obstetrics and Gynecology/Female Pelvic Medicine and Reconstructive Surgery |
657 ## - INDEX TERM--FUNCTION |
Medline publication type |
Journal Article |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Gutman, Robert E |
700 ## - ADDED ENTRY--PERSONAL NAME |
Local Authors |
Tefera, Eshetu |
790 ## - Authors |
All authors |
Cameron AP, Gutman RE, Jeppson PC, Khavari R, Kopcsay KS, Marczak TD, Tefera E |
856 ## - ELECTRONIC LOCATION AND ACCESS |
DOI |
<a href="https://dx.doi.org/10.1007/s00192-021-05030-3">https://dx.doi.org/10.1007/s00192-021-05030-3</a> |
Public note |
https://dx.doi.org/10.1007/s00192-021-05030-3 |
942 ## - ADDED ENTRY ELEMENTS (KOHA) |
Koha item type |
Journal Article |
Item type description |
Article |