Granular Cell Tumor of the Ascending Colon.

MedStar author(s):
Citation: Case Reports Gastroenterology. 17(1):104-108, 2023 Jan-Dec.PMID: 36820070Department: MedStar St Mary's HospitalForm of publication: Journal ArticleMedline article type(s): Case ReportsYear: 2023ISSN:
  • 1662-0631
Name of journal: Case reports in gastroenterologyAbstract: Granular cell tumor (GCT) was first described by Abrikossoff in 1926. It is a mostly benign tumor with rare malignant transformation. It is defined as a soft tissue neoplasm with abundant eosinophilic cytoplasm. The mean age of diagnosis for GCT is around 45 years. It is rare for GCT to be found in the gastrointestinal (GI) tract. Within the subset of GI tract, the colon is an extremely rare site for it to be found. Franburg-Smith histopathology criteria are used to differentiate a benign from a malignant GCT. The malignant form is aggressive with high recurrence rates after resection. Histopathology and immunohistochemical stains are used to make a definitive diagnosis. Herein, we present a rare case of an ascending colon polyp that was resected and found to be a benign GCT. Copyright © 2023 The Author(s). Published by S. Karger AG, Basel.All authors: Dhruv S, Atodaria KP, Gurala D, El Imad T, Abergel JFiscal year: FY2023Digital Object Identifier: Date added to catalog: 2023-04-11
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Granular cell tumor (GCT) was first described by Abrikossoff in 1926. It is a mostly benign tumor with rare malignant transformation. It is defined as a soft tissue neoplasm with abundant eosinophilic cytoplasm. The mean age of diagnosis for GCT is around 45 years. It is rare for GCT to be found in the gastrointestinal (GI) tract. Within the subset of GI tract, the colon is an extremely rare site for it to be found. Franburg-Smith histopathology criteria are used to differentiate a benign from a malignant GCT. The malignant form is aggressive with high recurrence rates after resection. Histopathology and immunohistochemical stains are used to make a definitive diagnosis. Herein, we present a rare case of an ascending colon polyp that was resected and found to be a benign GCT. Copyright © 2023 The Author(s). Published by S. Karger AG, Basel.

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