Clinical and silent stroke following aortic valve surgery and transcatheter aortic valve implantation. [Review]

MedStar author(s):
Citation: Cardiovascular Revascularization Medicine. 13(2):133-40, 2012 Mar-Apr.PMID: 22226171Institution: MedStar Heart & Vascular InstituteForm of publication: Journal ArticleMedline article type(s): Journal Article | Research Support, Non-U.S. Gov't | ReviewSubject headings: *Aortic Valve Stenosis/su [Surgery] | *Aortic Valve/su [Surgery] | *Heart Valve Prosthesis Implantation/ae [Adverse Effects] | *Stroke/ep [Epidemiology] | Aortic Valve Stenosis/mo [Mortality] | Cardiac Catheterization | Heart Valve Prosthesis Implantation/mt [Methods] | Humans | Risk Assessment | Risk Factors | Stroke/et [Etiology] | Survival Rate | World HealthLocal holdings: Available in print through MWHC library: 2002 - presentISSN:
  • 1878-0938
Name of journal: Cardiovascular revascularization medicine : including molecular interventionsAbstract: Transcatheter aortic valve implantation (TAVI) has been introduced as an alternative to conventional surgery for high-risk patients with aortic stenosis. A recently published randomized clinical trial demonstrated reduction of mortality in high-risk or inoperable patients when compared to medical treatment or balloon aortic valvuloplasty. Despite this evidence of superiority, the rate of TAVI complications is high, and perhaps the most devastating of the nonfatal complications is cerebral injury. This review will compare the incidence of stroke and "silent" cerebral injury after surgical aortic valve replacement and after TAVI and will discuss mechanisms that can lead to cerebral injury during these procedures and subsequently how to prevent this with new protection devices. Copyright 2012. Published by Elsevier Inc.All authors: Ben-Dor I, Hauville C, Lindsay J, Pichard AD, Waksman RDigital Object Identifier: Date added to catalog: 2013-09-17
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Journal Article MedStar Authors Catalog Article Available 22226171

Available in print through MWHC library: 2002 - present

Transcatheter aortic valve implantation (TAVI) has been introduced as an alternative to conventional surgery for high-risk patients with aortic stenosis. A recently published randomized clinical trial demonstrated reduction of mortality in high-risk or inoperable patients when compared to medical treatment or balloon aortic valvuloplasty. Despite this evidence of superiority, the rate of TAVI complications is high, and perhaps the most devastating of the nonfatal complications is cerebral injury. This review will compare the incidence of stroke and "silent" cerebral injury after surgical aortic valve replacement and after TAVI and will discuss mechanisms that can lead to cerebral injury during these procedures and subsequently how to prevent this with new protection devices. Copyright 2012. Published by Elsevier Inc.

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