The impact of tobacco use on preterm premature rupture of the membranes.

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Citation: American Journal of Perinatology. 30(3):185-90, 2013 Mar.PMID: 22930157Institution: MedStar Health Research InstituteForm of publication: Journal ArticleMedline article type(s): Journal Article | Research Support, N.I.H., ExtramuralSubject headings: *Fetal Membranes, Premature Rupture/ep [Epidemiology] | *Smoking/ep [Epidemiology] | Adolescent | Adult | Age Factors | Female | Humans | Incidence | Logistic Models | Multivariate Analysis | Pregnancy | Premature Birth/ep [Epidemiology] | Reproductive Tract Infections/ep [Epidemiology] | United States/ep [Epidemiology] | Vagina/mi [Microbiology] | Young AdultISSN:
  • 0735-1631
Name of journal: American journal of perinatologyAbstract: CONCLUSION: Our data do not support a significant relationship between tobacco use and pPROM. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.OBJECTIVE: To determine if tobacco use increases the incidence of preterm premature rupture of the membranes (pPROM) or alters perinatal outcomes after pPROM.RESULTS: There was no difference in the incidence of pPROM when comparing nonsmokers to those using tobacco. Although a trend was seen between the incidence of pPROM and the amount smoked, this did not reach statistical significance. Among the patients with pPROM, the use of tobacco was not associated with an increase in perinatal morbidity.STUDY DESIGN: This is a secondary analysis of the databases of three completed Eunice Kennedy Shriver National Institute of Child Health and Human Development-supported Maternal Fetal Medicine Units Network studies. Self-reported tobacco exposure data was obtained. Its relationship with the incidence of pPROM and associated neonatal outcome measures were assessed.All authors: Andres RL, Carey JC, Caritis SN, Dombrowski MP, Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network, Hauth JC, Iams JD, Klebanoff MA, Langer O, Leveno KJ, Miodovnik M, O'Sullivan MJ, Sibai B, Van Dorsten JP, Wapner RJ, Zhao YDigital Object Identifier: Date added to catalog: 2014-02-24
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Journal Article MedStar Authors Catalog Article Available 22930157

CONCLUSION: Our data do not support a significant relationship between tobacco use and pPROM. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

OBJECTIVE: To determine if tobacco use increases the incidence of preterm premature rupture of the membranes (pPROM) or alters perinatal outcomes after pPROM.

RESULTS: There was no difference in the incidence of pPROM when comparing nonsmokers to those using tobacco. Although a trend was seen between the incidence of pPROM and the amount smoked, this did not reach statistical significance. Among the patients with pPROM, the use of tobacco was not associated with an increase in perinatal morbidity.

STUDY DESIGN: This is a secondary analysis of the databases of three completed Eunice Kennedy Shriver National Institute of Child Health and Human Development-supported Maternal Fetal Medicine Units Network studies. Self-reported tobacco exposure data was obtained. Its relationship with the incidence of pPROM and associated neonatal outcome measures were assessed.

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