In-stent restenosis of drug-eluting stents. [Review]

MedStar author(s):
Citation: Future Cardiology. 9(5):721-31, 2013 Sep.PMID: 24020673Institution: MedStar Heart & Vascular InstituteForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Coronary Restenosis | *Drug-Eluting Stents | *Myocardial Revascularization/mt [Methods] | Coronary Angiography | Coronary Restenosis/et [Etiology] | Coronary Restenosis/ra [Radiography] | Coronary Restenosis/su [Surgery] | Humans | Prosthesis Failure | ReoperationISSN:
  • 1479-6678
Name of journal: Future cardiologyAbstract: Drug-eluting stents (DES) have emerged as an improved alternative to bare-metal stents by demonstrating reduced rates of restenosis and target lesion revascularization. This emergence has led to the unrestricted use of DES for various indications and lesions, and subsequently revealed DES in-stent restenosis as a novel interventional therapeutic dilemma. Recent insights regarding the patho-physiological processes and therapeutic alternatives have added to the accumulated knowledge regarding the appropriate approach to this phenomenon. This review aims to detail the mechanism and clinical presentation of, and therapeutic strategies for, the treatment of DES in in-stent restenosis.All authors: Minha S, Pichard AD, Waksman RDigital Object Identifier: Date added to catalog: 2014-08-21
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Journal Article MedStar Authors Catalog Article Available 24020673

Drug-eluting stents (DES) have emerged as an improved alternative to bare-metal stents by demonstrating reduced rates of restenosis and target lesion revascularization. This emergence has led to the unrestricted use of DES for various indications and lesions, and subsequently revealed DES in-stent restenosis as a novel interventional therapeutic dilemma. Recent insights regarding the patho-physiological processes and therapeutic alternatives have added to the accumulated knowledge regarding the appropriate approach to this phenomenon. This review aims to detail the mechanism and clinical presentation of, and therapeutic strategies for, the treatment of DES in in-stent restenosis.

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