Endocrine Changes in Obesity. [Review]

Citation: MDText.com, Inc.. 2000PMID: 25905281Institution: MedStar Washington Hospital CenterDepartment: Medicine/Endocrinology.Form of publication: Journal ArticleMedline article type(s): ReviewSubject headings: IN PROCESS -- NOT YET INDEXEDYear: 2000Abstract: Obesity can be associated with several endocrine alterations arising from changes in the hypothalamic-pituitary hormones axes. These include hypothyroidism, Cushing's disease, hypogonadism, and growth hormone deficiency. Besides its role in energy storage, adipose tissue has many other important functions that can be mediated through hormones or substances synthesized and released by adipocytes, including leptin and adiponectin. Further, obesity is also a common feature of polycystic ovarian syndrome with hyperinsulinemia being the primary etiological factor. Here, we provide an overview of several endocrine syndromes known to result in obesity and discuss the endocrine role of adipose tissue in conjunction to its association with hypothalamic-pituitary-endocrine axes. For complete coverage of all related areas of Endocrinology, please visit our on-line FREE web-text, WWW.ENDOTEXT.ORG. Copyright © 2000-2024, MDText.com, Inc.All authors: Ylli D, Sidhu S, Parikh T, Burman KDFiscal year: FY2000Date added to catalog: 2024-04-24
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Journal Article MedStar Authors Catalog Article 25905281 Available 25905281

Obesity can be associated with several endocrine alterations arising from changes in the hypothalamic-pituitary hormones axes. These include hypothyroidism, Cushing's disease, hypogonadism, and growth hormone deficiency. Besides its role in energy storage, adipose tissue has many other important functions that can be mediated through hormones or substances synthesized and released by adipocytes, including leptin and adiponectin. Further, obesity is also a common feature of polycystic ovarian syndrome with hyperinsulinemia being the primary etiological factor. Here, we provide an overview of several endocrine syndromes known to result in obesity and discuss the endocrine role of adipose tissue in conjunction to its association with hypothalamic-pituitary-endocrine axes. For complete coverage of all related areas of Endocrinology, please visit our on-line FREE web-text, WWW.ENDOTEXT.ORG. Copyright © 2000-2024, MDText.com, Inc.

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