Appropriateness of Plasma Transfusion: A College of American Pathologists Q-Probes Study of Guidelines, Waste, and Serious Adverse Events. [Review]

MedStar author(s):
Citation: Archives of Pathology & Laboratory Medicine. 141(3):396-401, 2017 MarPMID: 28234567Institution: MedStar Washington Hospital CenterDepartment: PathologyIN - Lehman, Christopher M. From the Department of Pathology and Laboratory Medicine, MedStar Washington Hospital Center, Washington, DC (Dr Alcorn); the Department of Pathology, Northwestern University, Chicago, Illinois (Dr Ramsey); Biostatistics, College of American Pathologists, Northfield, Illinois (Ms Souers); and the Department of Pathology, University of Utah, Salt Lake City (Dr Lehman). Dr Alcorn is now at Medical Division, Bloodworks, and Transfusion Service Labs, Swedish, Seattle, Washington.Form of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Blood Component Transfusion/st [Standards] | *Plasma | Humans | Practice Guidelines as TopicYear: 2017Local holdings: Available online from MWHC library: 1999 - present, Available in print through MWHC library: 1999 - 2006ISSN:
  • 0003-9985
Name of journal: Archives of pathology & laboratory medicineAbstract: CONCLUSIONS: - Most participating institutions are compliant with plasma transfusion guidelines based on published references, supported by appropriate testing. With transfusions for indications that lack evidence of efficacy and incidence of transfusion reactions, there is an ongoing role for transfusion service leaders to continue to update and monitor plasma transfusion practices.CONTEXT: - Plasma transfusion guidelines support patient care and safety, management of product wastage, and compliance; yet, there is little information across multiple institutions about use of and adherence to plasma transfusion guidelines.DESIGN: - The College of American Pathologists Q-Probes model was used to collect data from 89 participating institutions. Each site was asked to provide data relevant to its most recent 40 adult patient plasma transfusion episodes, and complete a questionnaire regarding plasma transfusion guidelines, utilization and wastage of plasma, and transfusion reactions related to plasma transfusion.OBJECTIVE: - To survey multiple institutions regarding their plasma transfusion guidelines and compliance, plasma wastage rates, and incidence of transfusion reactions associated with plasma transfusion.RESULTS: - The participating institutions reported a total of 3383 evaluable plasma transfusion episodes with transfusion of 9060 units of plasma. Compliance with institution-specific guidelines was seen in 3018 events (89%). Pretransfusion and posttransfusion coagulation testing was done in 3281 (97%) and 3043 (90%) of these episodes, respectively. Inappropriate criteria were noted for more than 100 transfusion episodes. Thirty-two plasma transfusion episodes (1%) were associated with a transfusion reaction. Serious and fatal reactions were reported. Median plasma wastage rate for the year preceding the study was 4.5%.All authors: Alcorn K, Lehman CM, Ramsey G, Souers RFiscal year: FY2017Digital Object Identifier: Date added to catalog: 2017-05-06
Holdings
Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article 28234567 Available 28234567

Available online from MWHC library: 1999 - present, Available in print through MWHC library: 1999 - 2006

CONCLUSIONS: - Most participating institutions are compliant with plasma transfusion guidelines based on published references, supported by appropriate testing. With transfusions for indications that lack evidence of efficacy and incidence of transfusion reactions, there is an ongoing role for transfusion service leaders to continue to update and monitor plasma transfusion practices.

CONTEXT: - Plasma transfusion guidelines support patient care and safety, management of product wastage, and compliance; yet, there is little information across multiple institutions about use of and adherence to plasma transfusion guidelines.

DESIGN: - The College of American Pathologists Q-Probes model was used to collect data from 89 participating institutions. Each site was asked to provide data relevant to its most recent 40 adult patient plasma transfusion episodes, and complete a questionnaire regarding plasma transfusion guidelines, utilization and wastage of plasma, and transfusion reactions related to plasma transfusion.

OBJECTIVE: - To survey multiple institutions regarding their plasma transfusion guidelines and compliance, plasma wastage rates, and incidence of transfusion reactions associated with plasma transfusion.

RESULTS: - The participating institutions reported a total of 3383 evaluable plasma transfusion episodes with transfusion of 9060 units of plasma. Compliance with institution-specific guidelines was seen in 3018 events (89%). Pretransfusion and posttransfusion coagulation testing was done in 3281 (97%) and 3043 (90%) of these episodes, respectively. Inappropriate criteria were noted for more than 100 transfusion episodes. Thirty-two plasma transfusion episodes (1%) were associated with a transfusion reaction. Serious and fatal reactions were reported. Median plasma wastage rate for the year preceding the study was 4.5%.

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