Association between Self-reported Masking Behavior and SARS-CoV-2 Infection Wanes from Pre-Delta to Omicron-Predominant Periods - North Carolina COVID-19 Community Research Partnership (NC-CCRP).
Citation: American Journal of Infection Control. 2022 Oct 06PMID: 36209944Institution: MedStar Health Research InstituteForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: IN PROCESS -- NOT YET INDEXEDYear: 2022ISSN:- 0196-6553
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
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Journal Article | MedStar Authors Catalog | Article | 36209944 | Available | 36209944 |
BACKGROUND: Wearing a face mask is a primary public health method to reduce SARS-CoV-2 transmission.
CONCLUSIONS: While the effect of not wearing a mask remains significant, during the Omicron-predominant period we observed a decrease in the association between self-reported mask wearing and risk of SARS-CoV-2 infection. Copyright © 2022. Published by Elsevier Inc.
METHODS: We performed a nested case-control analysis within the North Carolina COVID-19 Community Research Partnership (NC-CCRP) of adults who completed daily surveillance surveys, April 2020 - February 2022. We assessed the association between self-reported mask wearing behavior during non-household interactions and COVID-19 infection during three pandemic periods using conditional logistic regression models of risk of infection that were adjusted for demographics, vaccination status, and recent known exposure to COVID-19.
RESULTS: Among 3,901 cases and 27,813 date-matched controls, there was a significant interaction between mask use and time period (p<0.001). Prior to July 2021, the odds of a reported infection was 66% higher (aOR=1.66, 95% CI=1.43 - 1.91) among participants reporting >=1 day not wearing a mask compared to those who reported no days (1592 cases, 11717 controls). During the Delta-predominant period, the results were similar (aOR=1.53, 95% CI=1.23 - 1.89; 659 cases, 4649 controls). This association was attenuated during the Omicron-predominant period, where odds of an infection was 16% higher (aOR=1.16, 95% CI=1.03 - 1.32; 1563 cases, 10960 controls).
English