Implications of Clostridium septicum in vascular surgery: a case report and outcomes literature review.
Publication details: 2017; ISSN:- 0890-5096
- *Adenocarcinoma/mi [Microbiology]
- *Aneurysm, Infected/su [Surgery]
- *Aortic Aneurysm, Abdominal/su [Surgery]
- *Blood Vessel Prosthesis Implantation
- *Clostridium Infections/su [Surgery]
- *Clostridium septicum/ip [Isolation & Purification]
- *Colonic Neoplasms/mi [Microbiology]
- Adenocarcinoma/dg [Diagnostic Imaging]
- Adenocarcinoma/su [Surgery]
- Adult
- Aged
- Aged, 80 and over
- Aneurysm, Infected/dg [Diagnostic Imaging]
- Aneurysm, Infected/mi [Microbiology]
- Anti-Bacterial Agents/tu [Therapeutic Use]
- Aortic Aneurysm, Abdominal/dg [Diagnostic Imaging]
- Aortic Aneurysm, Abdominal/mi [Microbiology]
- Aortography/mt [Methods]
- Biopsy
- Clostridium Infections/dg [Diagnostic Imaging]
- Clostridium Infections/mi [Microbiology]
- Colectomy
- Colonic Neoplasms/dg [Diagnostic Imaging]
- Colonic Neoplasms/su [Surgery]
- Colonoscopy
- Computed Tomography Angiography
- Early Detection of Cancer/mt [Methods]
- Female
- Humans
- Male
- Middle Aged
- Treatment Outcome
- MedStar Washington Hospital Center
- Surgery
- Journal Article
| Item type | Current library | Collection | Call number | Status | Date due | Barcode | |
|---|---|---|---|---|---|---|---|
| Journal Article | MedStar Authors Catalog | Article | 28479472 | Available | 28479472 |
Available online from MWHC library: 1995 - present, Available in print through MWHC library:1999-2007
Clostridium septicum is a rare organism, accounting for approximately 1.3% of clostridial infections and is associated with synchronous colonic malignancy. This case report describes a patient successfully treated for a mycotic aortic aneurysm secondary to C. septicum bacteremia. Subsequent evaluation confirmed a colonic malignancy, prompting early intervention. A systematic literature review revealing a rate of gastrointestinal malignancy in this patient population is 71%, hematologic malignancy is 3.9%, with the remaining cohort of patients having an unknown source. Infectious involvement of the aorta and associated vascular structures portends a poor prognosis with a 57% mortality rate. Our case and updated review demonstrates the implications of C. septicum vascular seeding and subsequent treatment outcomes.
Copyright (C) 2017 Elsevier Inc. All rights reserved.
English