Reference ranges for rotational thromboelastometry in male Sprague Dawley rats.
Citation: Thrombosis Journal [Electronic Resource]. 15:31, 2017PMID: 29299031Institution: MedStar Health Research Institute | MedStar Washington Hospital CenterDepartment: Firefighters' Burn and Surgical Research Laboratory | SurgeryForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: PubMed-not-MEDLINE -- Not indexedYear: 2017Local holdings: Available online through MWHC library: 2003 - presentISSN:- 1477-9560
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
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Journal Article | MedStar Authors Catalog | Article | 29299031 | Available | 29299031 |
Available online through MWHC library: 2003 - present
Background: A functional coagulation assay was used to investigate the extrinsic pathway of coagulation on citrated whole blood samples from healthy adult male Sprague Dawley rats using the mini cup and pin system.
Conclusions: These reference ranges can be used in future studies in rats to identify clinically significant coagulopathies.
Methods: Reference values for coagulation parameters from forty-three animals were calculated using data obtained from the ROTEM delta hemostasis analyzer with the EXTEM test.
Results: The following ranges, presented as the 2.5-97.5 percentiles, were established: CT [18-77], CFT [20-80], alpha [73-86], MCF [53-70], and ML [1-22], along with others.
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