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Comparison of relationships between four common anthropometric measures and incident diabetes.

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Citation: Diabetes Research & Clinical Practice. 132:36-44, 2017 Jul 22PMID: 28783531Institution: MedStar Health Research InstituteForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Anthropometry/mt [Methods] | *Diabetes Mellitus, Type 2/et [Etiology] | Body Mass Index | Diabetes Mellitus, Type 2/ep [Epidemiology] | Female | Humans | Male | Middle Aged | Prospective Studies | RiskYear: 2017 ISSN:

0168-8227

Name of journal: Diabetes research and clinical practiceAbstract: AIMS: First, to conduct a detailed exploration of the prospective relations between four commonly used anthropometric measures with incident diabetes and to examine their consistency across different population subgroups. Second, to compare the ability of each of the measures to predict five-year risk of diabetes.CONCLUSIONS: Despite suggestions that abdominal measures of obesity have stronger associations with incident diabetes and better predictive accuracy than BMI, we found no overall advantage in any one measure at discriminating the risk of developing diabetes. Any of these measures would suffice to assist in primary diabetes prevention efforts. Copyright (c) 2017 Elsevier B.V. All rights reserved.METHODS: We conducted a meta-analysis of individual participant data on body mass index (BMI), waist circumference (WC), waist-hip and waist-height ratio (WHtR) from the Obesity, Diabetes and Cardiovascular Disease Collaboration. Cox proportional hazard models were used to estimate the association between a one standard deviation increment in each anthropometric measure and incident diabetes. Harrell's concordance statistic was used to test the predictive accuracy of each measure for diabetes risk at five years.RESULTS: Twenty-one studies with 154,998 participants and 9342 cases of incident diabetes were available. Each of the measures had a positive association with incident diabetes. A one standard deviation increment in each of the measures was associated with 64-80% higher diabetes risk. WC and WHtR more strongly associated with risk than BMI (ratio of hazard ratios: 0.95 [0.92,0.99] - 0.97 [0.95,0.98]) but there was no appreciable difference between the four measures in the predictive accuracy for diabetes at five years.All authors: Adams R, Barrett-Connor E, Boyko EJ, Eliasson M, Franco LJ, Fujimoto WY, Gonzalez C, Howard BV, Huxley RR, Jacobs DR Jr, Keinanen-Kiukaanniemi S, Lee CMY, Magliano D, Obesity, Diabetes and Cardiovascular Disease Collaboration, Pandeya N, Schreiner P, Shaw JE, Stevens J, Taylor A, Tuomilehto J, Wagenknecht L, Woodward MFiscal year: FY2018Digital Object Identifier:

https://dx.doi.org/10.1016/j.diabres.2017.07.022

Date added to catalog: 2017-08-23

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Item type	Current library	Collection	Call number	Status	Date due	Barcode
Journal Article	MedStar Authors Catalog	Article	28783531	Available		28783531

AIMS: First, to conduct a detailed exploration of the prospective relations between four commonly used anthropometric measures with incident diabetes and to examine their consistency across different population subgroups. Second, to compare the ability of each of the measures to predict five-year risk of diabetes.

CONCLUSIONS: Despite suggestions that abdominal measures of obesity have stronger associations with incident diabetes and better predictive accuracy than BMI, we found no overall advantage in any one measure at discriminating the risk of developing diabetes. Any of these measures would suffice to assist in primary diabetes prevention efforts. Copyright (c) 2017 Elsevier B.V. All rights reserved.

METHODS: We conducted a meta-analysis of individual participant data on body mass index (BMI), waist circumference (WC), waist-hip and waist-height ratio (WHtR) from the Obesity, Diabetes and Cardiovascular Disease Collaboration. Cox proportional hazard models were used to estimate the association between a one standard deviation increment in each anthropometric measure and incident diabetes. Harrell's concordance statistic was used to test the predictive accuracy of each measure for diabetes risk at five years.

RESULTS: Twenty-one studies with 154,998 participants and 9342 cases of incident diabetes were available. Each of the measures had a positive association with incident diabetes. A one standard deviation increment in each of the measures was associated with 64-80% higher diabetes risk. WC and WHtR more strongly associated with risk than BMI (ratio of hazard ratios: 0.95 [0.92,0.99] - 0.97 [0.95,0.98]) but there was no appreciable difference between the four measures in the predictive accuracy for diabetes at five years.

English