Outcome of Transcatheter Aortic Valve Implantation in Patients with Peripheral Vascular Disease.
Citation: American Journal of Cardiology. 124(3):416-422, 2019 Aug 01.PMID: 31174835Institution: MedStar Washington Hospital CenterDepartment: Medicine/Internal MedicineForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Aortic Valve Stenosis/su [Surgery] | *Peripheral Vascular Diseases/ep [Epidemiology] | *Transcatheter Aortic Valve Replacement | Acute Kidney Injury/ep [Epidemiology] | Aged, 80 and over | Aortic Valve Stenosis/ep [Epidemiology] | Blood Transfusion/sn [Statistics & Numerical Data] | Databases, Factual | Female | Hospital Mortality | Humans | Male | Matched-Pair Analysis | Pacemaker, Artificial/sn [Statistics & Numerical Data] | Postoperative Complications/ep [Epidemiology] | Retrospective Studies | Stroke/ep [Epidemiology] | United States/ep [Epidemiology]Year: 2019Local holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006ISSN:- 0002-9149
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
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Journal Article | MedStar Authors Catalog | Article | 31174835 | Available | 31174835 |
Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
Copyright (c) 2019 Elsevier Inc. All rights reserved.
Peripheral vascular disease (PVD) is common in patients referred for transcatheter aortic valve implantation (TAVI). We sought to investigate the impact of PVD on patients who underwent TAVI. Using data from the National Inpatient Sample database 2011 and 2014, we identified patients who had undergone TAVI. We studied the clinical characteristics and procedural outcomes in patients with PVD who underwent TAVI compared with those patients without PVD using propensity score matching score matching. Results: A total of 42,215 patients underwent TAVI; of which 1,388 patients were matched using propensity score matched scores to 694 in each (PVD vs no PVD) patients. The population had a mean age of 81 years old and 55.8% were of female gender. African-Americans constituted 4.3%. PVD patients who underwent TAVI were found to have higher rates of vascular complications (11.8% vs 5.9 % p <0.001) compared with non-PVD patients and tended to have higher mortality (5.5% vs 3.6%, p=0.121) and post-TAVI bleeding (13.5% vs 12% p=0.143). In conclusion, PVD patients have higher in-hospital mortality and higher incidence of in-hospital overall complications compared with patients who have no PVD.
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