Outcome of Transcatheter Aortic Valve Implantation in Patients with Peripheral Vascular Disease.

MedStar author(s):
Citation: American Journal of Cardiology. 124(3):416-422, 2019 Aug 01.PMID: 31174835Institution: MedStar Washington Hospital CenterDepartment: Medicine/Internal MedicineForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Aortic Valve Stenosis/su [Surgery] | *Peripheral Vascular Diseases/ep [Epidemiology] | *Transcatheter Aortic Valve Replacement | Acute Kidney Injury/ep [Epidemiology] | Aged, 80 and over | Aortic Valve Stenosis/ep [Epidemiology] | Blood Transfusion/sn [Statistics & Numerical Data] | Databases, Factual | Female | Hospital Mortality | Humans | Male | Matched-Pair Analysis | Pacemaker, Artificial/sn [Statistics & Numerical Data] | Postoperative Complications/ep [Epidemiology] | Retrospective Studies | Stroke/ep [Epidemiology] | United States/ep [Epidemiology]Year: 2019Local holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006ISSN:
  • 0002-9149
Name of journal: The American journal of cardiologyAbstract: Copyright (c) 2019 Elsevier Inc. All rights reserved.Peripheral vascular disease (PVD) is common in patients referred for transcatheter aortic valve implantation (TAVI). We sought to investigate the impact of PVD on patients who underwent TAVI. Using data from the National Inpatient Sample database 2011 and 2014, we identified patients who had undergone TAVI. We studied the clinical characteristics and procedural outcomes in patients with PVD who underwent TAVI compared with those patients without PVD using propensity score matching score matching. Results: A total of 42,215 patients underwent TAVI; of which 1,388 patients were matched using propensity score matched scores to 694 in each (PVD vs no PVD) patients. The population had a mean age of 81 years old and 55.8% were of female gender. African-Americans constituted 4.3%. PVD patients who underwent TAVI were found to have higher rates of vascular complications (11.8% vs 5.9 % p <0.001) compared with non-PVD patients and tended to have higher mortality (5.5% vs 3.6%, p=0.121) and post-TAVI bleeding (13.5% vs 12% p=0.143). In conclusion, PVD patients have higher in-hospital mortality and higher incidence of in-hospital overall complications compared with patients who have no PVD.All authors: Al-Khadra Y, AlJaroudi W, Alraies MC, Bagur R, Banerjee S, Darmoch F, Grines CL, Kaki A, Kwok CS, Mamas M, Pacha HM, Pinto DS, Rab T, Soud MFiscal year: FY2020Digital Object Identifier: Date added to catalog: 2019-06-21
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Item type Current library Collection Call number Status Date due Barcode
Journal Article MedStar Authors Catalog Article 31174835 Available 31174835

Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006

Copyright (c) 2019 Elsevier Inc. All rights reserved.

Peripheral vascular disease (PVD) is common in patients referred for transcatheter aortic valve implantation (TAVI). We sought to investigate the impact of PVD on patients who underwent TAVI. Using data from the National Inpatient Sample database 2011 and 2014, we identified patients who had undergone TAVI. We studied the clinical characteristics and procedural outcomes in patients with PVD who underwent TAVI compared with those patients without PVD using propensity score matching score matching. Results: A total of 42,215 patients underwent TAVI; of which 1,388 patients were matched using propensity score matched scores to 694 in each (PVD vs no PVD) patients. The population had a mean age of 81 years old and 55.8% were of female gender. African-Americans constituted 4.3%. PVD patients who underwent TAVI were found to have higher rates of vascular complications (11.8% vs 5.9 % p <0.001) compared with non-PVD patients and tended to have higher mortality (5.5% vs 3.6%, p=0.121) and post-TAVI bleeding (13.5% vs 12% p=0.143). In conclusion, PVD patients have higher in-hospital mortality and higher incidence of in-hospital overall complications compared with patients who have no PVD.

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