MedStar Authors catalog › Details for: The effect of pelvic organ prolapse severity on improvement in overactive bladder symptoms after pelvic reconstructive surgery.
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The effect of pelvic organ prolapse severity on improvement in overactive bladder symptoms after pelvic reconstructive surgery.

by Miranne, Jeannine M.
Citation: International Urogynecology Journal. 24(8):1303-8, 2013 Aug..Journal: International urogynecology journal.ISSN: 0937-3462.Full author list: Miranne JM; Lopes V; Carberry CL; Sung VW.UI/PMID: 23229418.Subject(s): Aged | Aged, 80 and over | Cohort Studies | Comorbidity | Female | *Gynecologic Surgical Procedures/mt [Methods] | Humans | Logistic Models | Middle Aged | *Pelvic Floor/su [Surgery] | *Pelvic Organ Prolapse/ep [Epidemiology] | *Pelvic Organ Prolapse/su [Surgery] | Prevalence | Quality of Life | Reconstructive Surgical Procedures/mt [Methods] | Retrospective Studies | *Severity of Illness Index | Treatment Outcome | *Urinary Bladder, Overactive/ep [Epidemiology] | *Urinary Bladder, Overactive/su [Surgery] | Urinary Incontinence, Urge/ep [Epidemiology] | Urinary Incontinence, Urge/pc [Prevention & Control]Institution(s): MedStar Washington Hospital CenterDepartment(s): Obstetrics and GynecologyActivity type: Journal Article.Medline article type(s): Journal ArticleOnline resources: Click here to access online Digital Object Identifier: http://dx.doi.org/10.1007/s00192-012-2000-z (Click here) Abbreviated citation: Int Urogynecol J Pelvic Floor Dysfunct. 24(8):1303-8, 2013 Aug.Local Holdings: Available online through MWHC library: 2010 - present.Abstract: INTRODUCTION AND HYPOTHESIS: This study evaluates the effect of baseline pelvic organ prolapse (POP) severity on improvement in overactive bladder (OAB) symptoms after pelvic reconstructive surgery.Abstract: METHODS: We performed a retrospective cohort study of women with POP and OAB who underwent surgical correction of symptomatic apical and/or anterior POP. OAB was defined as an affirmative response to item #15 (urinary frequency) and/or item #16 (urge incontinence) of the Pelvic Floor Distress Inventory (PFDI). POP severity was dichotomized as Pelvic Organ Prolapse Quantification (POP-Q) stage 1-2 versus stage 3-4. Our primary outcome was complete resolution or improvement of urinary frequency or urge incontinence on the PFDI 12 months postoperatively.Abstract: RESULTS: At 12 months postoperative, 41 (89%) women with stage 1-2 POP versus 47 (85 %) with stage 3-4 POP reported improvement in urinary frequency (p=0.58). Thirty five (90 %) with stage 1-2 and 34 (85 %) with stage 3-4 POP reported improvement in urge incontinence (p=0.74). On multiple logistic regression, women with stage 3-4 POP had a decreased odds of improvement in frequency or urge incontinence compared with women with stage 1-2 POP (adjusted odds ration [AOR]=0.06 [95 % CI 0.01-0.67]), after adjusting for confounders.Abstract: CONCLUSIONS: Women with coexisting POP and OAB who undergo surgical correction of POP experience improvement in OAB symptoms after surgery, although women with more severe POP may be at a higher risk of persistent frequency or urge incontinence.

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