A woman with warts, leg swelling, and deafness.
Citation: Journal of the American Academy of Dermatology. 71(3):577-80, 2014 Sep.PMID: 25128101Institution: MedStar Washington Hospital CenterDepartment: DermatologyForm of publication: Journal ArticleMedline article type(s): Case Reports | Journal Article | Research Support, N.I.H., IntramuralSubject headings: *GATA2 Transcription Factor/df [Deficiency] | *Hearing Loss, Sensorineural/im [Immunology] | *Immunologic Deficiency Syndromes/di [Diagnosis] | *Lymphedema/im [Immunology] | *Warts/im [Immunology] | Female | Humans | Middle AgedLocal holdings: Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006ISSN:- 0190-9622
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
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Journal Article | MedStar Authors Catalog | Article | Available | 25128101 |
Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
KEY TEACHING POINTS * We describe a 45-year-old woman with GATA2 deficiency associated with verrucae, lymphedema, immunodeficiency, and a history of infections and skin cancer. * GATA2 deficiency has variable clinical expressivity with differing presentations, including infection, hematopoietic abnormalities, immunodeficiency, lymphedema, and cancer. * Cutaneous manifestations include verruca vulgaris, soft tissue infections, lymphedema, and panniculitis. * Patients may have verrucae that can progress to squamous cell carcinomas; dermatologists therefore play an important role in managing these patients as members of a multidisciplinary team. Copyright Published by Mosby, Inc.
English